Research Journal of Pharmacy and Technology

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Effect of Liquid Media Height on the Pressure Drop during Production of Antibiotics in Bioreactor


Affiliations
1 Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, Chhattisgarh, India
2 Department of Mechanical Engineering, Vishwavidyalaya Engineering College, Sarguja University, Ambikapur, Chhattisgarh, India
     

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Three phase gas-liquid-solid systems are widely used by the pharmaceutical industries for the production of antibiotics such as patulin, penicillin, bacitracin etc. for which immobilized cell system or biofilms are used. During the process immobilized cells are fluidized in the liquid media using air. The present paper investigates regarding the dependency of the pressure drop on the height of liquid media present in the fluidizer.

Keywords

Immobilized Cell, Biofilm, Fluidization, Antibiotics, Bioreactor.
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  • Effect of Liquid Media Height on the Pressure Drop during Production of Antibiotics in Bioreactor

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Authors

S. Kumar
Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, Chhattisgarh, India
A. Arora
Department of Mechanical Engineering, Bhilai Institute of Technology, Durg, Chhattisgarh, India
H. Chandra
Department of Mechanical Engineering, Vishwavidyalaya Engineering College, Sarguja University, Ambikapur, Chhattisgarh, India

Abstract


Three phase gas-liquid-solid systems are widely used by the pharmaceutical industries for the production of antibiotics such as patulin, penicillin, bacitracin etc. for which immobilized cell system or biofilms are used. During the process immobilized cells are fluidized in the liquid media using air. The present paper investigates regarding the dependency of the pressure drop on the height of liquid media present in the fluidizer.

Keywords


Immobilized Cell, Biofilm, Fluidization, Antibiotics, Bioreactor.

References