Open Access
Subscription Access
Open Access
Subscription Access
Effect of Liquid Media Height on the Pressure Drop during Production of Antibiotics in Bioreactor
Subscribe/Renew Journal
Three phase gas-liquid-solid systems are widely used by the pharmaceutical industries for the production of antibiotics such as patulin, penicillin, bacitracin etc. for which immobilized cell system or biofilms are used. During the process immobilized cells are fluidized in the liquid media using air. The present paper investigates regarding the dependency of the pressure drop on the height of liquid media present in the fluidizer.
Keywords
Immobilized Cell, Biofilm, Fluidization, Antibiotics, Bioreactor.
Subscription
Login to verify subscription
User
Font Size
Information
- Morikawa, Y., Karube, I., and Suzuki, S. (1979). Penicillin G production by immobilized whole cells of Penicillium chrysogenum. Biotechnology and bioengineering, 21(2), 261-270.
- Epstein, N. (1981). Three-phase fluidization: Some knowledge gaps. The Canadian Journal of Chemical Engineering, 59(6), 649-657. doi:10.1002/cjce.545059060.
- Berk, D., Behie, L. A., Jones, A., Lesser, B. H., and Maurice Gaucher, G. (1984). The production of the antibiotic patulin in a three phase fluidized bed reactor I. Effect of medium composition. The Canadian Journal of Chemical Engineering, 62(1), 112-119.
- Nagamune, T., Endo, I., Kato, N., Nishimura, M., and Kobayashi, T. (1988). The effect of cultivation conditions on the penicillin production using a urethane foam-supported Penicillium chrysogenum. Bioprocess Engineering, 3(4), 173-176.
- Fan, L. S. (1989). Gas-liquid-solid fluidization engineering. Butterworths Series In Chemical Engineering Series.7,16-20.
- Kumar, S., Arora, A., and Chandar, H. (2017). Effect of variation in solid bed height on the pressure distribution during gas fluidization of solids. BITCON March 17.Durg, C.G.: Research Journal of Engineering Sciences (Res. J. Engineering Sci.). (Vol. 6 (7), 7-13).
- Kumar, S., Arora, A., and Chandra, H. (2017). Effect of Variation in Solid Bed Height on Fluctuation Ratio during Gas Fluidization of Solids in Stationary Liquid. International Journal for Research in Applied Science and Engineering Technology (IJRASET), 5(12), 1642-1649.
- Ruman, S., Kumar, S., Kundu, A., Ahmed, S., (2017). Computational Fluid Dynamic Analysis of Gas Solid Fluidization. International Journal of Innovative Research in Science, Engineering and Technology, 6(10), 19890-19898.
- Kumar, S., Arora, A., and Chandar, H. (2018). Effect of variation in size of solids on the pressure distribution during gas fluidization of solids. BITCON February 18.Durg, C.G.: International Journal of Advanced in Management, Technology and Engineering Sciences, 8(2), 645-654.
- Kumar, S., Arora, A., and Chandra, H. (2018). Effect of Solid Bed Height on Pressure Drop in Stationary Liquid Fluidization. International Journal of Technology (IJT). 8(1), 11-15.
- Kumar, S., Arora, A., and Chandra, H. (2018). Flow Regimes in Stationary Liquid Fluidization. International Journal of Technology (IJT). 8(1), 6-10.
Abstract Views: 191
PDF Views: 0