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Synthesis and Antimicrobial Activity of Some Sulfonamide Derivatives Containing Various Heterocyclic Moieties


Affiliations
1 Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq
     

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A series of new sulfonamide derivatives derived from N-(4-acetylphenyl)-4-methylbenzenesulfonamide bearing different heterocyclic moieties such as 1,3-thiazole, 2-azetidinone and 4- thiazolidinone. The newly synthesized sulfnamide derivatives have been characterized by FTIR, ¹H NMR, Mass spectra and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity and compared with reference drug Amoxicillin.

Keywords

Sulfonamide,1,3-Thiazole, 2-Azetidinone, 4-Thiazolidinone.
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  • Synthesis and Antimicrobial Activity of Some Sulfonamide Derivatives Containing Various Heterocyclic Moieties

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Authors

Olfat A. Nief
Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq
Zainab Z. Mahamad
Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq
Nahida A. Jinzeel
Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq
Firyal W. Askar
Department of Chemistry, College of Science, Mustansiriyah University, Baghdad, Iraq

Abstract


A series of new sulfonamide derivatives derived from N-(4-acetylphenyl)-4-methylbenzenesulfonamide bearing different heterocyclic moieties such as 1,3-thiazole, 2-azetidinone and 4- thiazolidinone. The newly synthesized sulfnamide derivatives have been characterized by FTIR, ¹H NMR, Mass spectra and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity and compared with reference drug Amoxicillin.

Keywords


Sulfonamide,1,3-Thiazole, 2-Azetidinone, 4-Thiazolidinone.

References