Research Journal of Pharmacy and Technology

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Antibacterial Activity of Essential Oils of Rosmarinus officinalis, Salvia officinalis and Anthemis nobilis Widespread in the Syrian Coast


Affiliations
1 Department of Microbiology and Biochemistry, Al Andalus University, Tartous, Syrian Arab Republic
2 Department of Pharmacognosy and Phytochemistry, Al Andalus University, Tartous, Syrian Arab Republic
3 Department of Pharmaceutical Chemistry and Quality Control, Al Andalus University, Tartous, Syrian Arab Republic
     

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We aimed in this study to determine the antibacterial efficacy of essential oils of Rosmarinus officinalis, Salvia officinalis leaves and Anthemis nobilis flowers widespread in the Syrian coast against several strains of Staphylococcus aureus and Pseudomonas aeruginosa. The essential oils were extracted and the yield was measured using Clevenger apparatus. In vitro investigation of antibacterial activity using agar disc diffusion method and minimal inhibitory concentration (MIC) of each essential oil was determined by microdilution method against studied bacteria. Results demonstrated that Rosmarinus officinalis essential oil had the highest activity (MIC for Staphylococcus aureus was 3.9μl/ml and MIC for Pseudomonas aeruginosa was 7.8 μl/ml). Salvia officinalis essential oil had moderate antibacterial effect with MIC of 31.2 μl/ml and 125μl/ml against Staphylococcus aureus and Pseudomonas aeruginosa respectively. On the other hand, Anthemis nobilis essential oil had no efficacy against tested bacterial strains. According to our study, Rosmarinus officinalis essential oil exhibited higher antibacterial activity against both Staphylococcus aureus and Pseudomonas aeruginosa than this of Salvia officinalis.

Keywords

Rosemary, Sage, Chamomile, Essential Oils, Antibacterial Activity, MIC.
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  • Antibacterial Activity of Essential Oils of Rosmarinus officinalis, Salvia officinalis and Anthemis nobilis Widespread in the Syrian Coast

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Authors

Rim M. Harfouch
Department of Microbiology and Biochemistry, Al Andalus University, Tartous, Syrian Arab Republic
Manal Darwish
Department of Pharmacognosy and Phytochemistry, Al Andalus University, Tartous, Syrian Arab Republic
Wisam Al-Asadi
Department of Pharmacognosy and Phytochemistry, Al Andalus University, Tartous, Syrian Arab Republic
Ali F. Mohammad
Department of Pharmaceutical Chemistry and Quality Control, Al Andalus University, Tartous, Syrian Arab Republic
Nour M. Gharib
Department of Microbiology and Biochemistry, Al Andalus University, Tartous, Syrian Arab Republic
Mohammad Haroun
Department of Pharmaceutical Chemistry and Quality Control, Al Andalus University, Tartous, Syrian Arab Republic

Abstract


We aimed in this study to determine the antibacterial efficacy of essential oils of Rosmarinus officinalis, Salvia officinalis leaves and Anthemis nobilis flowers widespread in the Syrian coast against several strains of Staphylococcus aureus and Pseudomonas aeruginosa. The essential oils were extracted and the yield was measured using Clevenger apparatus. In vitro investigation of antibacterial activity using agar disc diffusion method and minimal inhibitory concentration (MIC) of each essential oil was determined by microdilution method against studied bacteria. Results demonstrated that Rosmarinus officinalis essential oil had the highest activity (MIC for Staphylococcus aureus was 3.9μl/ml and MIC for Pseudomonas aeruginosa was 7.8 μl/ml). Salvia officinalis essential oil had moderate antibacterial effect with MIC of 31.2 μl/ml and 125μl/ml against Staphylococcus aureus and Pseudomonas aeruginosa respectively. On the other hand, Anthemis nobilis essential oil had no efficacy against tested bacterial strains. According to our study, Rosmarinus officinalis essential oil exhibited higher antibacterial activity against both Staphylococcus aureus and Pseudomonas aeruginosa than this of Salvia officinalis.

Keywords


Rosemary, Sage, Chamomile, Essential Oils, Antibacterial Activity, MIC.

References