Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Prevalence of Urinary Bacterial Colonisation in Women Seeking Obstetrical and Gynecological Support at a Secondary Care Centre in South India


Affiliations
1 Microbial Biotechnology Laboratory, School of Biosciences and Technology, Vellore Institute of Technology, Vellore - 632014, Tamil Nadu,, India
     

   Subscribe/Renew Journal


Asymptomatic bacteriuria is the presence of bacterial strains in urine samples obtained from a person without revelation of any symptoms of urinary infections. During pregnancy, women are prone to suffer from urinary tract infection at much higher rates due to certain physiological alterations. Thus, the awareness amongst women to protect themselves from asymptomatic bacteriuria and its risk factors are much required. The aim of this study was to determine the predominant uropathogens and their antibiotic susceptibility pattern isolated from women attending the outpatient department in Sri Narayani Hospital and Research Centre. Group of 350 patients were routinely checked. Urine samples of the patients were routinely collected and checked for presence of pathogenic bacteria. The microbes obtained were studied thoroughly to determine their pathogenicity. Antibiotic susceptibility ability of the organisms was studied to detect the resistance of the strains against the drugs used for the treatment. Escherichia coli and Klebsiella sp. were the two most predominantly found pathogens in the urine samples of patients suffering from asymptomatic bacteriuria.

Keywords

Antibiotic susceptibility, Asymptomatic bacteriuria, Patient, Uropathogens, Women.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Behzadi P, Behzadi E, Yazdanbod H, Aghapour R, Akbari Cheshmeh M, Salehian Omran D. A survey on urinary tract infections associated with the three most common uropathogenic bacteria. Maedica (Buchar) 2010; 5: 111–115.

  • Biadglegne F, Abera B. Antimicrobial resistance of bacterial isolates from urinary tract infections at Felge Hiwot Referral Hospital, Ethiopia. Ethiop J Health Dev. 2016; 23: 236–238.

  • Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A and Hooton TM. 2005. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis. 2005; 40: 643-654.

  • Ranjan A, Sridhar STK, Matta N, Chokkakula S, Ansari RK. Prevalence of UTI among Pregnant Women and Its Complications in Newborns. Indian J Pharm Pract. 2017; 10: 45.

  • Afoakwa P, Domfeh S, Afranie B, Owusu D, Donkor S, Sakyi K, Adom R, Kyeremeh G, Okyere B, Acheampong E, Amoah B. Asymptomatic Bacteriuria and Anti-Microbial Susceptibility Patterns among Women of Reproductive Age. A Cross-Sectional Study in Primary Care, Ghana. Medical Sciences. 2018; 6: 118.

  • Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Am J Med 2002; 113(suppl 1A): 5s–13s.

  • Kerure SB, Surpur R, Sagarad SS and Hegadi S. Asymptomatic bacteriuria among pregnant women. Int J Reprod Contracept Obstet Gynecol. 2013; 2: 213-216.

  • McAninch J, Lue TF. Smith and Tanagho’s General Urology. McGraw-Hill Professional; 2012.

  • Schmiemann G, Kniehl E, Gebhardt K, Matejczyk MM, Hummers-Pradier E. The diagnosis of urinary tract infection: a systematic review. Dtsch Arztebl Int. 2010; 107: 361–367.

  • Al Sweih N, Jamal W, Rotimi V. Spectrum and antibiotic resistance of uropathogens isolated from hospital and community patients with urinary tract infections in two large hospitals in Kuwait. Med Princ Pract. 2005; 14: 401–407.

  • Johnson J. Virulence factors in Escherichia coli urinary tract infection. Clin Microbiol Rev. 1991; 4: 80-128.

  • Podschun R, Ullmann U. Klebsiella spp. as Nosocomial Pathogens: Epidemiology, Taxonomy, Typing Methods, and Pathogenicity Factors. Clin Microbiol Rev. 1998; 11(4): 589-603.

  • Foxman B. The epidemiology of urinary tract infection. Nat Rev Urol. 2010; 7: 653-660.

  • Pezzlo M. Laboratory Diagnosis of Urinary Tract Infections: Guidelines, Challenges, and Innovations. Clin Microbiol Newsl. 2014; 36: 87-93.

  • Singh A, Jain S, Kumar D, Singh R, Bhatt H. Antimicrobial susceptibility pattern of extended-spectrum beta- lactamase producing Klebsiella pneumoniae clinical isolates in an Indian tertiary hospital. J Res Pharm Pract. 2015; 4: 153.

  • Williamson L, Parkes A, Wight D, Petticrew M, Hart G. Limits to modern contraceptive use among young women in developing countries: a systematic review of qualitative research. Reprod Health. 2009; 6: 3.

  • Jayahar BM, Ramakrishnan R, Vasu S, Meenakshi R, Palaniappan R. In-vitro efficacy of antibacterials against bacterial isolates from corneal ulcers. Indian J Ophthalmol. 2002; 50: 109-114.

  • Campoli-Richards DM, Monk JP, Price A, Benfield P, Todd PA, Ward A. Ciprofloxacin. Drugs. 1988; 35: 373-447.

  • Ruiz J, Castro D, Goni P, Santamaria JA, Borrego JJ, Vila J. Analysis of the mechanism of quinolone resistance in nalidixic acid-resistant clinical isolates of Salmonella serotype Typhimurium. J Med Microbiol. 1997; 46: 623-8.

  • Kow N, Holthaus E, Barber M. Bacterial uropathogens and antibiotic susceptibility of positive urine cultures in women with pelvic organ prolapse and urinary incontinence. Neurourol Urodyn. 2014; 35: 69-73.

  • Selman H, Mariani M, Barnocchi N, Mencacci A, Bistoni F, Arena S, Pizzasegale S, Brusco GF, Angelini A. Examination of bacterial contamination at the time of embryo transfer, and its impact on the IVF/pregnancy outcome. J Assist Reprod Genet. 2007; 24: 395-399.

  • Kalinderi K, Delkos D, Kalinderis M, Athanasiadis A, Kalogiannidis I. Urinary tract infection during pregnancy: current concepts on a common multifaceted problem. Journal of Obstetrics and Gynaecology. 2018; 38: 448-453.

  • Chatterjee A, Abraham J, Mary RR. Antibiotic profiling of Bacteria isolated from Sewage Soil Sample. Research Journal of Pharmacy and Technology. 2017; 10: 1053.

  • Chatterjee A, Nair S, Abraham J. Drug Resistance of Bacterial Isolates from Hospital Sewage Soil Sample. Research Journal of Pharmacy and Technology. (2018) ; 11: 2901-2905.


Abstract Views: 153

PDF Views: 0




  • Prevalence of Urinary Bacterial Colonisation in Women Seeking Obstetrical and Gynecological Support at a Secondary Care Centre in South India

Abstract Views: 153  |  PDF Views: 0

Authors

Devamani Pandian
Microbial Biotechnology Laboratory, School of Biosciences and Technology, Vellore Institute of Technology, Vellore - 632014, Tamil Nadu,, India
Jayanthi Abraham
Microbial Biotechnology Laboratory, School of Biosciences and Technology, Vellore Institute of Technology, Vellore - 632014, Tamil Nadu,, India

Abstract


Asymptomatic bacteriuria is the presence of bacterial strains in urine samples obtained from a person without revelation of any symptoms of urinary infections. During pregnancy, women are prone to suffer from urinary tract infection at much higher rates due to certain physiological alterations. Thus, the awareness amongst women to protect themselves from asymptomatic bacteriuria and its risk factors are much required. The aim of this study was to determine the predominant uropathogens and their antibiotic susceptibility pattern isolated from women attending the outpatient department in Sri Narayani Hospital and Research Centre. Group of 350 patients were routinely checked. Urine samples of the patients were routinely collected and checked for presence of pathogenic bacteria. The microbes obtained were studied thoroughly to determine their pathogenicity. Antibiotic susceptibility ability of the organisms was studied to detect the resistance of the strains against the drugs used for the treatment. Escherichia coli and Klebsiella sp. were the two most predominantly found pathogens in the urine samples of patients suffering from asymptomatic bacteriuria.

Keywords


Antibiotic susceptibility, Asymptomatic bacteriuria, Patient, Uropathogens, Women.

References