Research Journal of Pharmacy and Technology

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Study of Antifungal Activity of 2-methyl-3-(5'-aryl/Aryloxymethyl-1', 3', 4'-oxadiazol-2'-yl) Amino-1, 8-naphthyridines


Affiliations
1 Department of Chemistry,University College of Science, Mahatma Gandhi University, Nalgonda - 508544,, India
2 Sreenidhi Institute of Science and Technology (Autonomous) Yamnampet, Ghatkesar, Hyderabad - 501301, Telangana., India
     

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We here in report promising fungicidal activity of a series of 1, 8-naphthyridine semicarbazides and amino-Oxadiazole derivatives. The biological activity of semicarbazides and amino-Oxadiazole derivatives were synthesized and screened for their antifungal activity against Alternariaalternata, Fusariumoxysporum and Curvularialunata fungal strains and have received significant attention due to their distinctive antifungal activity and found to be more potent.

Keywords

Antifungal activity, Alternariaalternata, Fusariumoxysporum, Curvularialunata.
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  • Study of Antifungal Activity of 2-methyl-3-(5'-aryl/Aryloxymethyl-1', 3', 4'-oxadiazol-2'-yl) Amino-1, 8-naphthyridines

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Authors

Ramesh Domala
Department of Chemistry,University College of Science, Mahatma Gandhi University, Nalgonda - 508544,, India
Annapoorna R. Sapuri Butti
Department of Chemistry,University College of Science, Mahatma Gandhi University, Nalgonda - 508544,, India
Laxminarayana Eppakayla
Sreenidhi Institute of Science and Technology (Autonomous) Yamnampet, Ghatkesar, Hyderabad - 501301, Telangana., India

Abstract


We here in report promising fungicidal activity of a series of 1, 8-naphthyridine semicarbazides and amino-Oxadiazole derivatives. The biological activity of semicarbazides and amino-Oxadiazole derivatives were synthesized and screened for their antifungal activity against Alternariaalternata, Fusariumoxysporum and Curvularialunata fungal strains and have received significant attention due to their distinctive antifungal activity and found to be more potent.

Keywords


Antifungal activity, Alternariaalternata, Fusariumoxysporum, Curvularialunata.

References