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Oral-genital Lichenoid Reaction: A Rare Hypersensitives to Drug, a Review


Affiliations
1 Department of Health, Faculty of Vocational Studies, Universitas Airlangga,, Indonesia
2 Narizma Healthcare, Surabaya, Indonesia
3 HVA Hospital, Pare Kediri, East Java., Indonesia
4 Narizma Healthcare, Surabaya,, Indonesia
5 Deptartment of Dental Nursing, Politeknik Kesehatan Kementrian Kesehatan, Indonesia
     

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Background: Lichenoid reaction as the result of hypersensitivity from drug might be had similir clinical appearance to idiopathic lichen planus. Lichenoid drug reaction is termed as a condition of the oral cavity having an identifiable etiology, which is clinically and histologically similar to oral lichen planus and also manifest on genital. A number of drugs have been described as a causative factor of those reactive lesions. Objectives : The aim of this study is to finding mechanism of oral-genital lichenoid reaction caused by drugs. Problem Statement: Potential Pathway of Oral-genital lichenoid reaction caused by drugs. Discussion: Oral lichenoid lesions could be impact from medication and contact antigenic reaction. Clinical condition these two look similar to oral lichen planus, also its pathology. Studies of LDR caused by angiotensin-converting enzyme (ACE) inhibitors, antimalaria, antituberculosis, antitumor and non-steroidal anti-inflammatory drugs (NSAIDs) have been found. Conclusion: OLR is a disease condition with definite identifiable aetiology. Cell-mediated immune dysregulation has been associated with pathogenesis, explaining oral and genital manifestation.

Keywords

Lichenoid Reaction, Oral-genital, Drug, Hypersensitives.
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  • Oral-genital Lichenoid Reaction: A Rare Hypersensitives to Drug, a Review

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Authors

Nanda Rachmad Putra Gofur
Department of Health, Faculty of Vocational Studies, Universitas Airlangga,, Indonesia
Aisyah Rachmadani Putri Gofur
Narizma Healthcare, Surabaya, Indonesia
Rizki Nur Rachman Putra Gofur
HVA Hospital, Pare Kediri, East Java., Indonesia
Mega Kahdina
HVA Hospital, Pare Kediri, East Java., Indonesia
Hernalia Martadila Putri
Narizma Healthcare, Surabaya,, Indonesia
Soesilaningtyas
Deptartment of Dental Nursing, Politeknik Kesehatan Kementrian Kesehatan, Indonesia

Abstract


Background: Lichenoid reaction as the result of hypersensitivity from drug might be had similir clinical appearance to idiopathic lichen planus. Lichenoid drug reaction is termed as a condition of the oral cavity having an identifiable etiology, which is clinically and histologically similar to oral lichen planus and also manifest on genital. A number of drugs have been described as a causative factor of those reactive lesions. Objectives : The aim of this study is to finding mechanism of oral-genital lichenoid reaction caused by drugs. Problem Statement: Potential Pathway of Oral-genital lichenoid reaction caused by drugs. Discussion: Oral lichenoid lesions could be impact from medication and contact antigenic reaction. Clinical condition these two look similar to oral lichen planus, also its pathology. Studies of LDR caused by angiotensin-converting enzyme (ACE) inhibitors, antimalaria, antituberculosis, antitumor and non-steroidal anti-inflammatory drugs (NSAIDs) have been found. Conclusion: OLR is a disease condition with definite identifiable aetiology. Cell-mediated immune dysregulation has been associated with pathogenesis, explaining oral and genital manifestation.

Keywords


Lichenoid Reaction, Oral-genital, Drug, Hypersensitives.

References