Research Journal of Pharmacy and Technology

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Effect of Vitamin D Therapy on Adiponectin Level among Type 2 Diabetes Mellitus Patients


Affiliations
1 Nineveh Health Directorate, Mosul,, Iraq
2 College of Medicine, University of Mosul,, Iraq
3 College of Medicine, Ninevah University, Mosul,, Iraq
     

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The aim of this study was to investigate the effect of weekly dose of 50.000IU vitamin D for 8 weeks on serum adiponectin level in diabetic patients who have vitamin D deficiency. The study has been included 80 female and male patients with type 2 diabetes mellitus who have vitamin D deficiency were ages range from 25 to 70 years old. The patients have been prepared to have fasting serum adiponectin and vitamin D level tests. After 8 weeks of treatment with vitamin D as an add-on to the conventional anti-diabetic drugs taken up by the patients, there was a highly significant improvement in vitamin D and serum adiponectin level. The mean ±Std. of vitamin D at the base line was 14.76 ±6.02 ng/ml and after 8 weeks' treatment was 42.865 ±12.012 ng/ml. For adiponectin level, the mean ±Std. at the base line and after 8weeks treatment with vitamin D was 7.316 ±1.563 ng/ml, 9.705 ±3.269 ng/ml respectively. As a conclusion, vitamin D level corrected and became in sufficient values after treatment with 50.000IU vitamin D for 8 weeks. Also there is a highly significant improvement in serum adiponectin level after 8 weeks of vitamin D treatment.

Keywords

Vitamin D, Diabetes, Adiponectin, Insulin.
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  • Effect of Vitamin D Therapy on Adiponectin Level among Type 2 Diabetes Mellitus Patients

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Authors

Raghad A. Alkhaerow
Nineveh Health Directorate, Mosul,, Iraq
Shatha H. Mohammad
College of Medicine, University of Mosul,, Iraq
Nabeel N. Fadhil
College of Medicine, Ninevah University, Mosul,, Iraq

Abstract


The aim of this study was to investigate the effect of weekly dose of 50.000IU vitamin D for 8 weeks on serum adiponectin level in diabetic patients who have vitamin D deficiency. The study has been included 80 female and male patients with type 2 diabetes mellitus who have vitamin D deficiency were ages range from 25 to 70 years old. The patients have been prepared to have fasting serum adiponectin and vitamin D level tests. After 8 weeks of treatment with vitamin D as an add-on to the conventional anti-diabetic drugs taken up by the patients, there was a highly significant improvement in vitamin D and serum adiponectin level. The mean ±Std. of vitamin D at the base line was 14.76 ±6.02 ng/ml and after 8 weeks' treatment was 42.865 ±12.012 ng/ml. For adiponectin level, the mean ±Std. at the base line and after 8weeks treatment with vitamin D was 7.316 ±1.563 ng/ml, 9.705 ±3.269 ng/ml respectively. As a conclusion, vitamin D level corrected and became in sufficient values after treatment with 50.000IU vitamin D for 8 weeks. Also there is a highly significant improvement in serum adiponectin level after 8 weeks of vitamin D treatment.

Keywords


Vitamin D, Diabetes, Adiponectin, Insulin.

References