Research Journal of Pharmacy and Technology

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Exosome and Breast Cancer


Affiliations
1 Assistant Lecturer, Department of Therapeutic and Clinical Pharmacy, Baghdad College of Medical Sciences, Baghdad, Iraq
2 Assistant Lecturer, Department of Therapeutic and Clinical Pharmacy, Baghdad College of Medical Sciences, Baghdad –, Iraq
3 Lecturer, College of Pharmacy, Al Maaqal University, Basra, Iraq
     

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Breast cancer is responsible for the death of millions of women worldwide every year. It is widespread in the world and Iraq that become a genuine problem for public health. Several clinical, diagnostic and pathological techniques have been introduced to get early detection of breast tumors. The uses of current known tumors markers have many limitations. New technique for diagnosis of breast cancer involve detection of extracellular vesicles (EVs) exosomes and its phosphoproteins as a product of cancer cells which represent a non-invasive liquid biopsy that may replace the invasive surgical method.

Keywords

Breast cancer, Exosomes, Endosomes, Extracellular vesicles, Endosomal sorting complex required for transport (ESCRT) machinery.
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  • Exosome and Breast Cancer

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Authors

Yasir S J. Alrubaye
Assistant Lecturer, Department of Therapeutic and Clinical Pharmacy, Baghdad College of Medical Sciences, Baghdad, Iraq
Mohammed B. Mohammed
Assistant Lecturer, Department of Therapeutic and Clinical Pharmacy, Baghdad College of Medical Sciences, Baghdad –, Iraq
Haidar A. Abdulamir
Lecturer, College of Pharmacy, Al Maaqal University, Basra, Iraq

Abstract


Breast cancer is responsible for the death of millions of women worldwide every year. It is widespread in the world and Iraq that become a genuine problem for public health. Several clinical, diagnostic and pathological techniques have been introduced to get early detection of breast tumors. The uses of current known tumors markers have many limitations. New technique for diagnosis of breast cancer involve detection of extracellular vesicles (EVs) exosomes and its phosphoproteins as a product of cancer cells which represent a non-invasive liquid biopsy that may replace the invasive surgical method.

Keywords


Breast cancer, Exosomes, Endosomes, Extracellular vesicles, Endosomal sorting complex required for transport (ESCRT) machinery.

References