Hydrazinium salts of aromatic carboxylic acids were prepared by neutralization of acid with hydrazine hydrate and characterized by analytical, IR spectral and TG-DTA analysis. All the compounds undergo decomposition yielding carbon residue as the end product. The in vitro antibacterial study of 2,4-dichlorophenoxyacetic acid and its hydrazinium salt against Escherichia Coli have been investigated and the results show that the as-prepared hydrazinium salts have better antibacterial activity than the free acid.
Keywords
2,4-Dichlorophenoxyacetic Acid, Antibacterial Activity, Aromatic Carboxylic Acids, Hydrazinium Salt, IR spectral, TG – DTA.
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