Toxicology International (Formerly Indian Journal of Toxicology)

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Bisphenols as Human Health Hazard: A Systematic Review on Potent Sources, Route of Exposure, Harmful Effects and Safe Alternatives


Affiliations
1 Department of Food Science and Technology, Punjab Agricultural University, Ludhiana – 141004, Punjab, India
2 Department of Food, Technology and Nutrition, Lovely Professional University, Phagwara –144411, Punjab, India
     

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Bisphenols (BPs), as components of polycarbonates and laquer-coatings, are used for day to day household purposes, and frequent exposure has potential negative effects on each organ of the body, mostly evident by genetic changes and mitochondrial dysfunction. Children are at high risk due to higher accumulation per kg body weight which explicit toxic effect. Present strategies are to downsize exposure by replacing polycarbonates with wood, glass, stainless steel or green substitutes like bisguaiacol-F, soy protein isolate etc. At present, biodegradation by bacteria and fungus would be a great help to fight environmental bisphenols. It is necessary to come up with strong and functionally equivalent alternative to bisphenols which can safeguard future generations from further harmful effects.

Keywords

Bisphenols, Bisphenol A, Bisphenol B, Bisphenol S, Bisphenol Toxicity.
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  • Bisphenols as Human Health Hazard: A Systematic Review on Potent Sources, Route of Exposure, Harmful Effects and Safe Alternatives

Abstract Views: 346  |  PDF Views: 2

Authors

Ashwani Kumar
Department of Food Science and Technology, Punjab Agricultural University, Ludhiana – 141004, Punjab, India
Kritika Gupta
Department of Food, Technology and Nutrition, Lovely Professional University, Phagwara –144411, Punjab, India
Vidisha Tomer
Department of Food, Technology and Nutrition, Lovely Professional University, Phagwara –144411, Punjab, India
Amarjeet Kaur
Department of Food Science and Technology, Punjab Agricultural University, Ludhiana – 141004, Punjab, India
Vikas Kumar
Department of Food, Technology and Nutrition, Lovely Professional University, Phagwara –144411, Punjab, India

Abstract


Bisphenols (BPs), as components of polycarbonates and laquer-coatings, are used for day to day household purposes, and frequent exposure has potential negative effects on each organ of the body, mostly evident by genetic changes and mitochondrial dysfunction. Children are at high risk due to higher accumulation per kg body weight which explicit toxic effect. Present strategies are to downsize exposure by replacing polycarbonates with wood, glass, stainless steel or green substitutes like bisguaiacol-F, soy protein isolate etc. At present, biodegradation by bacteria and fungus would be a great help to fight environmental bisphenols. It is necessary to come up with strong and functionally equivalent alternative to bisphenols which can safeguard future generations from further harmful effects.

Keywords


Bisphenols, Bisphenol A, Bisphenol B, Bisphenol S, Bisphenol Toxicity.

References





DOI: https://doi.org/10.18311/ti%2F2018%2F22303