This research is aimed at determining and analysing the partial of the change of system reference and first level outpatient, the change of commitment-based capitation system, and the demand of accreditation in the era of National HealthCare on the work depression of medical and paramedical staffs of health centres in West Lombok. This research is casual study with primary and secondary data. The data were collected through questionnaires and interview. The population of this research are all 53 medical staffs and 480 paramedical staffs. The total population is 533 staffs. The samples were determined through stratified random sampling. The data were analyzed with multiple linear regression. The research showed that the system of reference of RJTP had positive and significant on the depression, commitment-based capitation system had positive and significant effect of the depression, accreditation had positive and significant effect of the depression. This research suggested that district government of West Lombok, especially Health Agency provide seminars and trainings for medical and paramedical staffs in West Lombok in order to be ready to anticipate the changes of policy of the central government. It is also necessary to recruit new medical and paramedical staffs for health centres in West Lombok, due to the new staff recruitment is for the adaptation to the new policy, and the service of health of community should always run as usual.
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