Proximate Analysis and the Assessment of the Level of Toxicity of Hexane, Ethyl Acetate and Methanol Extracts of Annona Muricata Aerial Part Using Brine Shrimp Lethality (Artemia Salina)

In This Research Work The Medicinal Plantannona Muricata Was Extracted With Three Different Solvents And The Extracts Were Subjected To Toxicity Test Using Brine Shrimp Lethality Test At Different Concentrations. At 100pm Concentration The Hexane Extract Gave 80.0% Mortality Rate, Ethyl Acetate Extract Gave 75.0% Mortality Rate And Methanol Extract Equallygave 75.0% Mortality Rate. The Extracts Showed Different Percentage Mortality Rates At Different Concentrations And The Methanol Extract Was Found To Exhibit The Most Significant Cytotoxicity Activity Against Brine Shrimp Artemia Salina With The Lethal Concentration Value (LC) Of 32.515µg/Ml. The Dried Plant Material Was Characterized For Proximate Analysis As To Determine Its Nutritional Composition And It Exhibited 2.0% Moisture Content, 7.40% Ash Content And 15.89% Crude Fibre Content. This Research Results Have Shown That The Plant Extracts were Toxic To Brine Shrimp Due To The Presence Of Bioactive Compounds Of Various Pharmacological Activities. This Is An Indication That The Plant Extracts Can Exhibit Good Anticancer Property When Tested Against Some Cancer Cell Lines.