![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextgreen.png)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextred.png)
![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextgreen.png)
![Open Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltext_open_medium.gif)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltextred.png)
![Restricted Access](https://i-scholar.in/lib/pkp/templates/images/icons/fulltext_restricted_medium.gif)
An RP-HPLC Method for the Estimation of Dexibuprofen in Pharmaceutical Tablet Dosage Form
Subscribe/Renew Journal
A reverse phase high performance liquid chromatography (RP-HPLC) method has been developed for the estimation of Dexibuprofen in bulk drug and pharmaceutical dosage forms. The quantification was carried out on Waters Symmetry C18 column in isocratic mode, with mobile phase consisting of Acetonitrile and water in the ratio of 55:45%(v/v), adjusted to pH 2.5 with orthophosphoric acid. The mobile phase was pumped at a rate of 1.5mL/min and detection was carried out at 214nm and linearity was found to be in the range of 40 to 160μg/mL. The correlation co-efficient was found to be 0.9991. The % recovery values were found to be in the range of 99.0 to 102%. Validation of the proposed method has also been done.
Keywords
Dexibuprofen, Isocratic, RP-HPLC, Estimation, Tablets.
Subscription
Login to verify subscription
User
Font Size
Information
![](https://i-scholar.in/public/site/images/abstractview.png)
Abstract Views: 414
![](https://i-scholar.in/public/site/images/pdfview.png)
PDF Views: 0