Asian Journal of Pharmacy and Technology

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Assessment of Phytochemical Screening, Antioxidant and Antibacterial Potential of the Methanolic Extract of Ricinus communis l.


Affiliations
1 Suresh Gyan Vihar University, Jaipur, India
2 Mahatma Gandhi Institute of Applied Sciences, JECRC Campus, Jaipur-22, India
     

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The medicinal plants represent a massive reservoir of probable microbial compounds that could be useful as a substitute to synthetic microbicides as well as are being used to develop drugs. In the present study, the powder extracts of Ricinus communis L. (Euphorbiaceae) were tested for their antioxidant activity by radical scavenging activity using 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) method and antibacterial acitivity against different bacteria i.e. Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum by disc diffusion method. Also, Phytochemical screening of methanolic extracts of Ricinus communis have been screened. Further, the antioxidant activity shows moderate to potent antioxidant activity, with the ED50 value i.e. 0.838 μg/ml. When screening for antimicrobial activity, the results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of methanolic extract was showed against Enterobacter and Aspergillus niger.

Keywords

Antioxidant Activity, Antimicrobial Activity, DPPH Scavenging,Ricinus communis
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  • Shariff, Z.U. (2001). Chemical composition and antimicrobial activity of the essential oils from the gum of Turkish Pistachio (Pistacia vera L.) J. Agric Food Chem. Jun 6: 52(12): 3911 – 3914.

  • Chung PY, Chung LY, Ngeow YF et al., 2004. Antimicrobial activities of Malaysian plant species. Pharm Bio 42: 292 – 300.

  • Nair R, Chanda SV., 2004. Antibacterial activity of some medicinal plants of Saurashtra region. J. Jissue Res 4: 117 – 120.

  • De N, Ifeoma, E (2002). Antimicrobial effects of components of the bark extracts of Neem. J. Technol. Dev., 8: 23 – 28.

  • Nair R, Kalariya T, Chanda S., 2005. Antibacterial activity of some selected Indian medicinal flora. Turk J Biol 29: 41 – 47.

  • Essawi T, Srour M., 2000. Screening of some palestnian medicinal plants for antibacterial activity J Ethnopharmacol 70: 343 – 349.

  • Mothana, R.A., Lindequist, U., 2005. Antimicrobial activity of some medicinal plants of the island soqotra. J.Ethnopharmacol., 96: 177 – 181.

  • Gill, L.S. 1988. Taxonomy of flowering plants, Africana – Feb publishers Ltd., Nigeria.

  • Pandey, B.P., (2006). A textbook of Botany: Angiosperms, Taxonomy, Anatomy, Embryology and Economic Botany, S. Chand and Co., Ltd., Ram Nagar, New Delhi.

  • Etukudo, I. 2003. Ethnobotany: Conventional and traditional uses of plants, verdict Press, Ugo, Akwa Ibom, Nigeria.

  • Vasishta, P.C 1974 Taxonomy of Angiosperms 2nd ed. R. Chand and Co. New Delhi.

  • Agbovie, T., Amponsah, K., Crentsil, O.R., Dennis, F. Odamtten, G.T. and ofusohene - Djan W. 2002. Conservation and sustainable use of medicine plants in Ghana, Ethnobotanical Survey, UNEP – WCMC, Cambridge, UK.

  • Betti, J.L. 2004, An ethnobotanical study of medicinal plants among the Baka pygmies in the Dja Biospher Reserve, Cameroon, Africa Study Monographs 25(1) : 1-27.

  • Kubmarawa, D., Ajoku, G.a. Eniverem, N.M and Okorie, D.A 2007 Preliminary Phytochemical and antimicrobial screening of 50 medicing plants from Nigeria, African J. Biotechnilogy 6(14): 1690 – 1696. Pandery, B.P. 2006. A text book of Bofancy: Angiosperms, Taxonomy, Anatomy, Embryology and Economic Botany, S.Chand and Co., Ltd., Ram Nagar, New Delhi.

  • Trease, G.F and Evans, W.C. 2002. Pharmacognosy, 15th Ed. Saunders.


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  • Assessment of Phytochemical Screening, Antioxidant and Antibacterial Potential of the Methanolic Extract of Ricinus communis l.

Abstract Views: 408  |  PDF Views: 1

Authors

Nidhi Rao
Suresh Gyan Vihar University, Jaipur, India
Sandhya Mittal
Suresh Gyan Vihar University, Jaipur, India
Sudhanshu
Suresh Gyan Vihar University, Jaipur, India
Ekta Menghani
Mahatma Gandhi Institute of Applied Sciences, JECRC Campus, Jaipur-22, India

Abstract


The medicinal plants represent a massive reservoir of probable microbial compounds that could be useful as a substitute to synthetic microbicides as well as are being used to develop drugs. In the present study, the powder extracts of Ricinus communis L. (Euphorbiaceae) were tested for their antioxidant activity by radical scavenging activity using 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) method and antibacterial acitivity against different bacteria i.e. Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum by disc diffusion method. Also, Phytochemical screening of methanolic extracts of Ricinus communis have been screened. Further, the antioxidant activity shows moderate to potent antioxidant activity, with the ED50 value i.e. 0.838 μg/ml. When screening for antimicrobial activity, the results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of methanolic extract was showed against Enterobacter and Aspergillus niger.

Keywords


Antioxidant Activity, Antimicrobial Activity, DPPH Scavenging,Ricinus communis

References