Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Microwave-Assisted Synthesis and Antibacterial Activity of Some New Flavones and 1, 5-Benzothiazepines


Affiliations
1 P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
     

   Subscribe/Renew Journal


The synthesis of heterocyclic compounds containing flavones (4a-i) and 1,5-benzothiazepines (5a-i) from chalcone derivatives containing 3,4-methylenedioxy phenyl ring using microwave irradiation in 80-97% yield within 2-4 min. The work-up is simple, shorter reaction time, increase in reaction rate with better yields. The structures of synthetic compounds have been characterized using IR and 1H NMR spectral data together with halogen analysis. All synthesized compounds have been screened for their antibacterial activity.

Keywords

Chalcones, Flavones, 1,5-Benzothiazepines, Microwave Irradiation, Antibacterial Activity.
Subscription Login to verify subscription
User
Notifications
Font Size


Abstract Views: 193

PDF Views: 0




  • Microwave-Assisted Synthesis and Antibacterial Activity of Some New Flavones and 1, 5-Benzothiazepines

Abstract Views: 193  |  PDF Views: 0

Authors

V. A. Navale
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
S. S. Mokle
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
Archana Y. Vibhute
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
K. G. Karamunge
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
S. V. Khansole
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
S. B. Junne
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India
Y. B. Vibhute
P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), India

Abstract


The synthesis of heterocyclic compounds containing flavones (4a-i) and 1,5-benzothiazepines (5a-i) from chalcone derivatives containing 3,4-methylenedioxy phenyl ring using microwave irradiation in 80-97% yield within 2-4 min. The work-up is simple, shorter reaction time, increase in reaction rate with better yields. The structures of synthetic compounds have been characterized using IR and 1H NMR spectral data together with halogen analysis. All synthesized compounds have been screened for their antibacterial activity.

Keywords


Chalcones, Flavones, 1,5-Benzothiazepines, Microwave Irradiation, Antibacterial Activity.