Synthesis and Characterization of Biologically Active Mixed Ligand Complexes of 8-hydroxyquinoline and Salicylaldehyde

In this communication the synthesis of mixed ligand transition metal complexes of Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with 8-hydroxyquinoline as a primary ligand and salicylaldehyde as a secondary ligand is reported. The synthesized complexes were characterized using instrumental techniques IR, UV, Magnetic measurements and conductivity measurements in DMSO. All complexes show very low conductance values indicating their non electrolytic nature and they have an octahedral geometry. These complexes have been screened in vitro for their antimicrobial activity. In the present series of mixed ligand metal complexes, the Cu(II) Complex (C17H13Cl2CuNO3) and Zn(II) Complex (C17H13Cl2ZnNO3) showed good antibacterial as well as antifungal activity