Asian Journal of Research in Chemistry

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Synthesis and Characterization of Biologically Active Mixed Ligand Complexes of 8-hydroxyquinoline and Salicylaldehyde


Affiliations
1 School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
2 Yeshwant Mahavidyalaya, Nanded-431605, Maharashtra State, India
3 School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
     

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In this communication the synthesis of mixed ligand transition metal complexes of Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with 8-hydroxyquinoline as a primary ligand and salicylaldehyde as a secondary ligand is reported. The synthesized complexes were characterized using instrumental techniques IR, UV, Magnetic measurements and conductivity measurements in DMSO. All complexes show very low conductance values indicating their non electrolytic nature and they have an octahedral geometry. These complexes have been screened in vitro for their antimicrobial activity. In the present series of mixed ligand metal complexes, the Cu(II) Complex (C17H13Cl2CuNO3) and Zn(II) Complex (C17H13Cl2ZnNO3) showed good antibacterial as well as antifungal activity

Keywords

Mixed Ligand Complex, 8-hydroxyquinoline, Salicylaldehyde, Antimicrobial Activity
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  • Synthesis and Characterization of Biologically Active Mixed Ligand Complexes of 8-hydroxyquinoline and Salicylaldehyde

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Authors

Dnyaneshwar S. Wankhede
School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
P. A. Kulkarni
Yeshwant Mahavidyalaya, Nanded-431605, Maharashtra State, India
Nikhil S. Jadhav
School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
Manisha D. Gurle
School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
Pradip B. Wagh
School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India
Omkar Shankarrao
School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India

Abstract


In this communication the synthesis of mixed ligand transition metal complexes of Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with 8-hydroxyquinoline as a primary ligand and salicylaldehyde as a secondary ligand is reported. The synthesized complexes were characterized using instrumental techniques IR, UV, Magnetic measurements and conductivity measurements in DMSO. All complexes show very low conductance values indicating their non electrolytic nature and they have an octahedral geometry. These complexes have been screened in vitro for their antimicrobial activity. In the present series of mixed ligand metal complexes, the Cu(II) Complex (C17H13Cl2CuNO3) and Zn(II) Complex (C17H13Cl2ZnNO3) showed good antibacterial as well as antifungal activity

Keywords


Mixed Ligand Complex, 8-hydroxyquinoline, Salicylaldehyde, Antimicrobial Activity

References