Asian Journal of Research in Pharmaceutical Sciences

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A Comparative Evaluation of the Antioxidant Activity of Some Medicinal Plants Popularly Used in India


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1 Sri Indu Institute of Pharmacy, Sheiguda, R.R. Dist, 5010510, India
     

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The methanolic crude extracts of some commonly used medical plants were screened for their free radical scavenging properties using ascorbic acid as standard antioxidant. Free radical scavenging activity was evaluated using 1,1- diphenyl-2-picryl-hydrazyl (DPPH) free radical. The overall antioxidant activity of green tea (Camellia sinensis linn.) was the strongest, follows in descending order by black tea (Camellia sinesis linn.),Eugenia caryophyllus (spreng), Piper cubeba linn., Zea mays and Piper nigrum,. All the methanolic extracts exhibited antioxidant activity significantly. The IC50 of the methanolic extracts ranged between 6.7±0.1 and 144.1±2.2 and that of ascorbic acid was 8.9±0.1μg/ml. the study reveals that the consumption of these spices would exert several beneficial effects by virtue of their antioxidant activity.

Keywords

Antioxidant, DPPH, Ascorbic Acid, Free Radical Scavenging Activity.
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Abstract Views: 474

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  • A Comparative Evaluation of the Antioxidant Activity of Some Medicinal Plants Popularly Used in India

Abstract Views: 474  |  PDF Views: 2

Authors

Ch. Madhu
Sri Indu Institute of Pharmacy, Sheiguda, R.R. Dist, 5010510, India
J. Swapna
Sri Indu Institute of Pharmacy, Sheiguda, R.R. Dist, 5010510, India
K. Neelima
Sri Indu Institute of Pharmacy, Sheiguda, R.R. Dist, 5010510, India
Monic V. Shah
Sri Indu Institute of Pharmacy, Sheiguda, R.R. Dist, 5010510, India

Abstract


The methanolic crude extracts of some commonly used medical plants were screened for their free radical scavenging properties using ascorbic acid as standard antioxidant. Free radical scavenging activity was evaluated using 1,1- diphenyl-2-picryl-hydrazyl (DPPH) free radical. The overall antioxidant activity of green tea (Camellia sinensis linn.) was the strongest, follows in descending order by black tea (Camellia sinesis linn.),Eugenia caryophyllus (spreng), Piper cubeba linn., Zea mays and Piper nigrum,. All the methanolic extracts exhibited antioxidant activity significantly. The IC50 of the methanolic extracts ranged between 6.7±0.1 and 144.1±2.2 and that of ascorbic acid was 8.9±0.1μg/ml. the study reveals that the consumption of these spices would exert several beneficial effects by virtue of their antioxidant activity.

Keywords


Antioxidant, DPPH, Ascorbic Acid, Free Radical Scavenging Activity.

References