Current Science

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Cadmium is an extremely toxic heavy metal and causes neurotoxicity by inducing oxidative stress and membrane disturbances in brain. Phyllanthus emblica and Lycopodium 200c have anti-oxidative properties and are able to remove the cadmium-produced free radicals. This study investigates the role of Lycopodium 200c and Phyllanthus emblica (amlaki) in ameliorating the toxic effects of cadmium on the brain of mice. Swiss albino mice were used and divided into four different sets with one control, one induced, one with amlaki and other with both amlaki and Lycopodium treatment. To observe the changes, tests for brain acetylcholinesterase along with Mg2+ ATPase activities were performed. Results show that cadmium toxicity leads to decrease in enzymatic activities which can be reversed by the effects of amlaki and Lycopodium 200c.

Keywords

Antioxidative Properties, Cadmium, Free Radicals, Oxidative Stress, Toxicity.
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