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What can be said about the Annual Review that has not been stated before? All of us know that the series contains articles on, to use those two cliches, 'cutting edge' information on the 'state-of-theart' of medical research. It has, quite deservedly, among the highest impact factors among the periodicals, in all of the subjects that the series covers. This volume too, joins the others in the pathology series as an outstanding one.
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