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Polarity, Asymmetry and Aging:Are there Yayatis among Bacteria?


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1 Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pune 411 008, India
 

Bacteria have been shown to age. In an exponentially growing population some cells progressively slow down and stop dividing. This is thought to be due to asymmetric damage segregation in which old pole cells retain damaged components and the new pole cells receive newly synthesized components. Polarity implies functional asymmetry with a predefined direction with or without morphological difference. Cellular polarity and division asymmetry are common to yeast, bacteria and stem cells of multi-cell organisms. A number of processes in bacteria, including formation of endospores, flagella, stalks or buds show clear polar biases.
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  • Stewart, E. J., Madden, R., Paul, G. and Taddei, F., PLoS Biol., 2005, 3, 295–300.

  • Ackermann, M., Stearns, S. C. and Jenal, U., Science, 2003, 300, 1920.

  • Macara, I. G. and Mili, S., Cell, 2008, 135, 801–812.

  • Cameron, T. A., Zupan, J. R. and Zambryski, P. C., Trends Microbiol., 2015, 23, 347–353.

  • Lindner, A. B., Madden, R., Demarez, A., Stewart, E. J. and Taddei, F., Proc. Natl. Acad. Sci. USA, 2008, 105, 3076–3081.

  • Baig, U. I., Bhadbhade, B. J., Mariyam, D. and Watve, M. G., PLoS One, 2014, 9, e107445.

  • Chao, L., Rang, C. U., Proenca, A. M. and Chao, J. U., PLoS Comput Biol., 2016, 12, e1004700.

  • Watve, M., Parab, S., Jogdand, P. and Keni, S., Proc. Natl. Acad. Sci. USA, 2006, 103, 14831–14835.

  • Kysela, D. T., Brown, P. J. B., Huang, K. C. and Brun, Y. V., Annu. Rev. Microbiol., 2013, 67, 417–435.

  • Vedel, S., Nunns, H., Košmrlj, A., Semsey, S. and Trusina, A., Cell Syst., 2016, 3, 187–198.

  • Lele, U. N., Baig, U. I. and Watve, M. G., PLoS One, 2011, 6, e14516.

  • Turke, P. W., Q. Rev. Biol., 2008, 83, 243–256.

  • Baig, U., Sunny, R., Watve, M. and Lele, U., Matters, 2016, 2, e201603000022.

  • Wang, P., Robert, L., Pelletier, J., Dang, W. L., Taddei, F., Wright, A. and Jun, S., Curr. Biol., 2010, 20, 1099–1103.

  • Nakaoka, H. and Yuichi, W., BioRxiv., 2017, 1, 128298.

  • Bergmiller, T. et al., Science, 2017, 356, 311–315.

  • Leszczynska, D., Matuszewska, E., KuczynskaWisnik, D., Furmanek-Blaszk, B. and Laskowska, E., PLoS One, 2013, 8, e54737.


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  • Polarity, Asymmetry and Aging:Are there Yayatis among Bacteria?

Abstract Views: 410  |  PDF Views: 114

Authors

Ulfat Baig
Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pune 411 008, India
Milind Watve
Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pune 411 008, India
Uttara Lele
Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pune 411 008, India

Abstract


Bacteria have been shown to age. In an exponentially growing population some cells progressively slow down and stop dividing. This is thought to be due to asymmetric damage segregation in which old pole cells retain damaged components and the new pole cells receive newly synthesized components. Polarity implies functional asymmetry with a predefined direction with or without morphological difference. Cellular polarity and division asymmetry are common to yeast, bacteria and stem cells of multi-cell organisms. A number of processes in bacteria, including formation of endospores, flagella, stalks or buds show clear polar biases.

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DOI: https://doi.org/10.18520/cs%2Fv113%2Fi04%2F553-554