Research Journal of Animal Husbandry & Dairy Science

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Polyherbal Hypocholesterolemic Supplement Lowers Egg Yolk Cholesterol Without Affecting Performance and Egg Quality in Layers


Affiliations
1 Department of Poultry Science, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
2 Department of Physiology, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
3 Department of Biochemistry, KNP College of Veterinary Science, Shirwal (MAFSU), Satara (M.S.), India
4 Department of Veterinary Public Health, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
5 Ayurvet Ltd., Solan (H.P.), India
     

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This study was designed to evaluate efficacy of polyherbal hypocholesterolemic supplement AV/HLP/16 (test compound) on serum and egg yolk cholesterol levels and egg quality parameters in layers. One hundred and twenty healthy White Leghorn (BV 300 strain) of 54 weeks age were randomly divided into four treatments (T0, T1, T2, T3); subdivided into three replicates with ten birds in each replicate for a period of five weeks (54th to 58th weeks of age). T0 was the control supplied with commercial basal diet without addition of test compound. T1, T2 and T3 were supplemented with test compound in basal diet @ 1.0, 1.5 and 2.0 kg/ton of feed, respectively. Weekly feed intake, daily egg production, egg weights, egg yolk total cholesterol, egg weight, shape index, yolk weight, albumen weight, shell weight, shell thickness was recorded. Significant reduction in serum cholesterol and egg yolk cholesterol (P<0.05) was observed in treatment groups. Polyherbal AV/HLP/ 16 supplementation in layers did not impart any beneficial or deleterious effect on feed intake, feed efficiency, hen day egg production or egg quality traits viz., egg weight, shape index, yolk weight, and albumen weight except shell thickness. Polyherbal hypocholesterolemic supplement AV/HLP/16 @ 1.0, 1.5 and 2.0 kg per ton of feed reduced egg yolk cholesterol with better egg shell thickness without affecting the performance as well as egg quality parameters in layers.

Keywords

Layer, Hypocholesterolemic Supplement, Cholesterol.
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  • Abbas, R.J. (2010). Effect of using fenugreek, parsley and sweet basil seeds as feed additives on the performance of broiler chickens. Internat. J. Poult. Sci., 9 : 278-282.

  • Anila, L. and Vijayalakshami, N.R. (2002). Flavonoids from Emblica offincinalis and Mangifera indica-effectiveness for dyslipidemia. J. Ethnopharmacol., 79 : 81-87.

  • Baldwa, V.S., Bhasin, V., Ranka, P.C. and Mathur, K.M. (1981). Effects of Commiphora mukul (Guggul) in experimentally induced hyperlipemia and atherosclerosis. J. Asso. Physici. India., 29 : 13-17.

  • Balevi, T. and Coskun, B. (2004). Effects of dietary copper on production and egg cholesterol content in laying hens. Britis Poult. Sci., 45 : 530-534.

  • Carter, T.C. (1968). The hen egg: A mathematical model with three parameters. Brit. Poult. Sci., 9 : 165-171.

  • Chowdhury, S.R., Chowdhury, S.D. and Smith, T.K. (2002). Effect of dietary garlic on cholesterol metabolism in laying hens. Poult. Sci., 81 : 1856-1862.

  • Deng, R., Yang, D., Radke, A., Yang, J. and Yan, B. (2007). The hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: Dominance of transactivation over farsenoid Xreceptor-mediated antagonism. J. Pharmacol. Exp. Ther., 320 : 1153-1162.

  • Duncan, D.B. (1955). Multiple range and multiple F Test. Biometrics., 11 : 1-42.

  • Elangovan, A.V., Tyagi, P. K., Mandal, A.B., Tyagi, P.K. and Deo, C. (2011). Effect of dietary supplementation of certain herbal agents and cholesterol lowering drug on egg production performance and egg quality of Japanese Quail Layers. Indian J. Poult. Sci., 46 : 316-319.

  • Elkin, R.G., Yen, Z.H., Donkin, S.S., Story, J.A., Anderson, M., Newton. R.S. and Zhong, Y. (1999). Select 3-methylglutarryl-Co-A reductase inhibitors vary in their ability to reduce egg yolk cholesterol levels in laying hens through alteration of hepatic cholesterol biosynthesis and plasma VLDL composition. J. Nutr.,129:1010-1019.

  • Ferri, N., Kohei, Y., Sadilek, M., Rodolfo, P., Rafael, A.C., Michael, H. and Alberto, C. (2003). Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation. Britis J. Pharmacol., 138 : 811-818.

  • Haust, H.L. and Beveridge, J.M.R. (1996). Type and quantity of 3/3-hydroxysterols excreted by subjects subsisting on formula rations high in corn oil. J. Nutr., 81 : 13.

  • Herrmann, G.R. and Samawi, A. (1962). The effects of various serum cholesterol lowering procedures and agents in patients with coronary artery disease. Tex. Rep. Biol. Med., 20 : 599.

  • Kanduri, A.B., Saxena, M.J., Ravikanth, K., Maini, S. and Dandale, M. (2013). Hypocholesterolemic effect of herbal supplement on serum and egg yolk cholesterol in layer poultry. Internat. J. Biol. Pharm. & Allied Sci., 2 : 1199-1202.

  • Kim, J.H., Hong, S.T, Lee, H.S. and Kim, H.J. (2004). Oral administration of pravastatin reduces egg cholesterol but not plasma cholesterol in laying hens. Poult. Sci., 83 : 1539-1543.

  • Khan, S.H., Hasan, S., Sardar, R. and Anjum, M.A. (2008). Effects of dietary garlic powder on cholesterol concentration in Native Desi laying hens. Am. J. Food Technol., 3 : 207-213.

  • Konjufca, V.H., Pesti, G.M. and Bakalli, R.I. (1997). Modulation of cholesterol level in broiler meat by dietary garlic and copper. Poult. Sci., 76 : 1264-1271.

  • Lien, T.E., Chen, K.L., Wu, C.P. and Lu, J.J. (2004). Effects of supplemental copper and chromium on the serum and egg traits of laying hens. Britis Poult. Sci., 45 : 535-539.

  • Lonkar, V.D., Jalaludeen, A., Narayankutty, K. and Viswanath, A. (2009). Modulation of cholesterol level in broiler chicken by feeding garlic (Allium sativum) powder and neem (Azadirachta indica) seed cake. Indian J. Poult. Sci., 44 : 49-53.

  • Mathur, R., Sharma, A., Dixit, V.P. and Varma, M. (1996). Hypolipidaemic effect of fruit juice ofEmblica officinalis in cholesterolfed rabbits. J. Ethnopharmacol., 50 : 61-68.

  • Merat, A. and Fallahzadeh, M. (1996). Effect of garlic on some blood lipids and HMG-CoA reductase activity. Iran. J. Med. Sci., 21 : 141-146.

  • Mori, A.V., Mendonca, Jr., X-de, C.and Santosh, C.O.F. (1999). Effect of dietary lipid lowering drugs upon lipid and egg yolk cholesterol levels of laying hens. J. Agri. Food Chem., 47 : 31-35.

  • Mottaghitalab, M. and Taraz, Z. (2004). Garlic powder as blood serum and egg yolk cholesterol lowering agent. Poult. Sci., 41 : 50-57. Peterson, D.W. (1951). Effect of soybean sterols in the diet on plasma and liver cholesterol in chicks. Proc. Societ. Exp. Biol. Med., 78 : 143-147.

  • Pollak, O.J. (1953). Reduction of blood cholesterol in man.Circulation. 7 : 702-706.

  • Premkumar, K., Saminathan, P. and Viswanathan, K. (2002). Effect of supplementation of Copper and Garlic on blood and meat cholesterol in broilers. Indian J. Poult. Sci., 37 : 252-257.

  • Raj, P.M., Narahari, D. and Balaji, N.S. (2013). Production of eggs with enriched nutritional value (Designer Eggs) using feeds containing herbal supplements. Internat. J. Vet. Sci., 2 : 99-102.

  • Satyavati, G.V., Dwarakanath, C. and Tripathi, S.N. (1969). Experimental studies on the hypocholesterolemic effect of Commiphora mukul. Engl. (Guggul). Indian J. Med. Res., 57 : 1950-1962.

  • Sauvaire, Y., Ribes, G., Baccou, J.C. and Loubatieres-Mairian, M.M. (1991). Implication of steroid saponins and sapogenins in hypocholesterolemic effect of fenugreek. Lipids., 26 : 191-197.

  • Schan, H. (1959). Sterol-balance experiments in humans.Nature, 184: 1872.

  • Sharma, R.K., Elangovan, A.V., Mandal, A.B., Tyagi, P.K. and

  • Shrivastav, A.K. (2009). Response of white leghorn hens to certain herbs in diets on production performance, blood and egg cholesterol. Indian. J. Poult. Sci., 44 : 347-351.

  • Sowmya, P. and Rajalakshmi, P. (1999). Hypocholesterolemic effect off germinated fenugreek seeds in human subjects.Plant Foods Human Nutr., 53 : 359-365.

  • Urizar, N.L., Liverman, A.B., Dodds, D.T., Silva, F.V., Ordentlich, P., Yan,Y., Gonzalez, F.J., Heyman, R. A., Mangelsdorf, D.J. and Moore, D.D. (2002). A natural product that lowers cholesterol as an antagonist ligand for FXR. Sci., 296 : 1703-1706.

  • Wybenga, D.R., Pileggi, V.J., Dirstine, P.H. and Giorgio, J.D. (1970). Direct manual determination of serum total cholesterol with single stable reagent. Clin. Chem., 16 : 980-984.

  • https://www.google.co.in/search?hl=en-IN&gbv=2&q=related: www.ncbi.nlm.nih.gov/pmc/articles/PMC1206007/+Herrmann, + G.R. per cent 3B + Samawi + A. + 1962. + The + effects + of + various + serum + cholesterol + lowering + procedures + and + agents + in + patients + with + coronary + artery + disease. + Texas + Report + on + Biology + and ++ Medicine, + 20: 599& tbo = 1& sa = X&ei= Dr5tVKbpBob6yATRt4L4Cw&ved=0CBYQHzAA


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  • Polyherbal Hypocholesterolemic Supplement Lowers Egg Yolk Cholesterol Without Affecting Performance and Egg Quality in Layers

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Authors

V. D. Lonkar
Department of Poultry Science, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
A. S. Kadam
Department of Poultry Science, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
V. R. Patodkar
Department of Physiology, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
S. N. Jadhav
Department of Biochemistry, KNP College of Veterinary Science, Shirwal (MAFSU), Satara (M.S.), India
R. P. Kolhe
Department of Veterinary Public Health, KNP College of Veterinary Science (MAFSU), Shirwal, Satara (M.S.), India
Shivi Maini
Ayurvet Ltd., Solan (H.P.), India

Abstract


This study was designed to evaluate efficacy of polyherbal hypocholesterolemic supplement AV/HLP/16 (test compound) on serum and egg yolk cholesterol levels and egg quality parameters in layers. One hundred and twenty healthy White Leghorn (BV 300 strain) of 54 weeks age were randomly divided into four treatments (T0, T1, T2, T3); subdivided into three replicates with ten birds in each replicate for a period of five weeks (54th to 58th weeks of age). T0 was the control supplied with commercial basal diet without addition of test compound. T1, T2 and T3 were supplemented with test compound in basal diet @ 1.0, 1.5 and 2.0 kg/ton of feed, respectively. Weekly feed intake, daily egg production, egg weights, egg yolk total cholesterol, egg weight, shape index, yolk weight, albumen weight, shell weight, shell thickness was recorded. Significant reduction in serum cholesterol and egg yolk cholesterol (P<0.05) was observed in treatment groups. Polyherbal AV/HLP/ 16 supplementation in layers did not impart any beneficial or deleterious effect on feed intake, feed efficiency, hen day egg production or egg quality traits viz., egg weight, shape index, yolk weight, and albumen weight except shell thickness. Polyherbal hypocholesterolemic supplement AV/HLP/16 @ 1.0, 1.5 and 2.0 kg per ton of feed reduced egg yolk cholesterol with better egg shell thickness without affecting the performance as well as egg quality parameters in layers.

Keywords


Layer, Hypocholesterolemic Supplement, Cholesterol.

References