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Preliminary Phytochemical Screening and Antioxidant Activity of Petroleum Ether Extract of Trichosanthes dioica Roxb (Fruits)


Affiliations
1 30, Gomati Colony, Nehru Nagar, Bhopal (M.P.), India
2 Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India
     

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In-vitro antioxidant activity of petroleum ether extract of Trichosanthes dioica was determined by DPPH free radical scavenging assay, Reducing power assay, Nitric oxide scavenging activity, Hydrogen peroxide radical scavenging activity using ascorbic acid as a standard. The IC50 values were calculated for all the models in order to evaluate the antioxidant efficiency of Trichosanthes dioica extract. In all the testing a significant correlation existed between concentration of the extract and % inhibition of free radicals. Obtained results clearly indicated that petroleum ether extract of Trichosanthes dioica possesses significant antioxidant potential as compared with standard.


Keywords

Trichosanthes dioica, Nitric Oxide, % Inhibition.
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  • Preliminary Phytochemical Screening and Antioxidant Activity of Petroleum Ether Extract of Trichosanthes dioica Roxb (Fruits)

Abstract Views: 224  |  PDF Views: 0

Authors

Yogesh Shivhare
30, Gomati Colony, Nehru Nagar, Bhopal (M.P.), India
Priya Singh
Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India
K. K. Patel
Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India
Prashant Soni
Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), India

Abstract


In-vitro antioxidant activity of petroleum ether extract of Trichosanthes dioica was determined by DPPH free radical scavenging assay, Reducing power assay, Nitric oxide scavenging activity, Hydrogen peroxide radical scavenging activity using ascorbic acid as a standard. The IC50 values were calculated for all the models in order to evaluate the antioxidant efficiency of Trichosanthes dioica extract. In all the testing a significant correlation existed between concentration of the extract and % inhibition of free radicals. Obtained results clearly indicated that petroleum ether extract of Trichosanthes dioica possesses significant antioxidant potential as compared with standard.


Keywords


Trichosanthes dioica, Nitric Oxide, % Inhibition.