Preliminary Phytochemical Screening and Antioxidant Activity of Petroleum Ether Extract of Trichosanthes dioica Roxb (Fruits)

In-vitro antioxidant activity of petroleum ether extract of Trichosanthes dioica was determined by DPPH free radical scavenging assay, Reducing power assay, Nitric oxide scavenging activity, Hydrogen peroxide radical scavenging activity using ascorbic acid as a standard. The IC₅₀ values were calculated for all the models in order to evaluate the antioxidant efficiency of Trichosanthes dioica extract. In all the testing a significant correlation existed between concentration of the extract and % inhibition of free radicals. Obtained results clearly indicated that petroleum ether extract of Trichosanthes dioica possesses significant antioxidant potential as compared with standard.