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Evaluation of Antimicrobial Activity of Tephrosia procumbens Buch–Ham


Affiliations
1 Dept. of Pharmacognosy, Luqman College of Pharmacy, Behind P and T Quarters, Old Jewargi Road, Gulbarga 585102, India
2 HKES’s Society’s College of Pharmacy, Gulbarga, India
3 Luqman College of Pharmacy, Gulbarga, India
4 Allana College of Pharmacy, Pune, India
     

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In the present study, the entire plant of Tephrosia procumbens Buch-Ham commonly known as Vempalli, Indigo sauvage (Fam-Fabaceae/ Leguminosae) was investigated for the phytochemical screening and antimicrobial property against certain microorganisms using disc diffusion method. The entire plant of Tephrosia procumbens were collected, shade dried at room temperature, pulverized and extracted with 95% ethanol in soxhlet extractor to get total ethanolic extract which is further fractionated with the solvents of different polarities. Total aqueous extract was also obtained by macerating the shade dried material with 3% of chloroform water I.P. All the extracts and fractions were subjected for Preliminary Phytochemical screening, which has shown the presence of Carbohydrates, Steroids and Flavonoids and evaluation of antimicrobial property by using disc diffusion method on various pathogenic forms of microorganisms including gram positive, gram negative and fungi. It was found that total ethanolic and total aqueous extract of entire plant of Tephrosia procumbens significantly inhibit the growth of microorganisms as compared to standard drugs Gentamycin and streptomycin (Hi-Media Lab. Mumbai).

Keywords

Tephrosia procumbens, Antimicrobial Activity.
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  • Evaluation of Antimicrobial Activity of Tephrosia procumbens Buch–Ham

Abstract Views: 270  |  PDF Views: 0

Authors

Faheem I. Patwekar
Dept. of Pharmacognosy, Luqman College of Pharmacy, Behind P and T Quarters, Old Jewargi Road, Gulbarga 585102, India
Sanjeev Heroor
HKES’s Society’s College of Pharmacy, Gulbarga, India
Mohsina F. Patwekar
Luqman College of Pharmacy, Gulbarga, India
Muhammad Asif
Allana College of Pharmacy, Pune, India

Abstract


In the present study, the entire plant of Tephrosia procumbens Buch-Ham commonly known as Vempalli, Indigo sauvage (Fam-Fabaceae/ Leguminosae) was investigated for the phytochemical screening and antimicrobial property against certain microorganisms using disc diffusion method. The entire plant of Tephrosia procumbens were collected, shade dried at room temperature, pulverized and extracted with 95% ethanol in soxhlet extractor to get total ethanolic extract which is further fractionated with the solvents of different polarities. Total aqueous extract was also obtained by macerating the shade dried material with 3% of chloroform water I.P. All the extracts and fractions were subjected for Preliminary Phytochemical screening, which has shown the presence of Carbohydrates, Steroids and Flavonoids and evaluation of antimicrobial property by using disc diffusion method on various pathogenic forms of microorganisms including gram positive, gram negative and fungi. It was found that total ethanolic and total aqueous extract of entire plant of Tephrosia procumbens significantly inhibit the growth of microorganisms as compared to standard drugs Gentamycin and streptomycin (Hi-Media Lab. Mumbai).

Keywords


Tephrosia procumbens, Antimicrobial Activity.