Research Journal of Pharmacology and Pharmacodynamics

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Anti-Ovulatory and Abortifacient Potential of the Ethanolic Extract of Henna Roots in Rats


Affiliations
1 Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India
     

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The rise in population in the developing world is over whelming and this intensifies the need for effective birth control measures. The synthetic agents available today for fertility control produce severe side effects. Such as hormonal imbalance, hypertension, increased risk of cancer and weight gain. Thus there is a need to replace these agents by safe and effective agents such as plants based contraceptive agents.

Therefore, the present study was under taken to explore the abotifacient and antiovulatory activity of ethanol extract of henna ischolar_mains. Thus, the successive ethanolic extract showed promising strong abotifacient and antiovulatory activity was observed at dose level of 400mg/kg body weight. Histological studies were carried out to confirm this effect.


Keywords

Abortifacient, Ovulation, Contraception.
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  • Anti-Ovulatory and Abortifacient Potential of the Ethanolic Extract of Henna Roots in Rats

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Authors

S. Rani
Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India
R. Manavalan
Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India
D. Kilimozhi
Department of Pharmacy, Annamalai University, Annamalai Nagar-608002, Tamil Nadu, India

Abstract


The rise in population in the developing world is over whelming and this intensifies the need for effective birth control measures. The synthetic agents available today for fertility control produce severe side effects. Such as hormonal imbalance, hypertension, increased risk of cancer and weight gain. Thus there is a need to replace these agents by safe and effective agents such as plants based contraceptive agents.

Therefore, the present study was under taken to explore the abotifacient and antiovulatory activity of ethanol extract of henna ischolar_mains. Thus, the successive ethanolic extract showed promising strong abotifacient and antiovulatory activity was observed at dose level of 400mg/kg body weight. Histological studies were carried out to confirm this effect.


Keywords


Abortifacient, Ovulation, Contraception.

References