Research Journal of Pharmacology and Pharmacodynamics

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Antinephrotoxic Effect of Boerhaavia diffusa L. Root on Lead Acetate Induced Nephrotoxicity in Male Albino Rats


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1 PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Sundarakkottai, Mannargudi-614016, Tamil Nadu, India
     

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Many Nephroprotective herbal preparations have been recommended in Indian systems of medicine for the treatment of neprotic disorders. Protective action of Boerhaavia diffusa extract (BDE) was evaluated in the animal model of Nephrotoxicity induced by lead acetate. Kidney marker enzymes and antioxidant enzymes were changed in lead acetate intoxicated rats. Boerhaavia diffusa extract brought about a moderate changes in the activities of all the above said levels. The present observation suggested that the treatment with Boerhaavia diffusa extract enhance the recovery from lead acetate induced nephrotic damage due to its nephroprotective activity.
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  • Antinephrotoxic Effect of Boerhaavia diffusa L. Root on Lead Acetate Induced Nephrotoxicity in Male Albino Rats

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Authors

N. Vaidegi
PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Sundarakkottai, Mannargudi-614016, Tamil Nadu, India
R. Anuradha
PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Sundarakkottai, Mannargudi-614016, Tamil Nadu, India

Abstract


Many Nephroprotective herbal preparations have been recommended in Indian systems of medicine for the treatment of neprotic disorders. Protective action of Boerhaavia diffusa extract (BDE) was evaluated in the animal model of Nephrotoxicity induced by lead acetate. Kidney marker enzymes and antioxidant enzymes were changed in lead acetate intoxicated rats. Boerhaavia diffusa extract brought about a moderate changes in the activities of all the above said levels. The present observation suggested that the treatment with Boerhaavia diffusa extract enhance the recovery from lead acetate induced nephrotic damage due to its nephroprotective activity.

References