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Nanoemulsion: Current State and perspectives


Affiliations
1 Department of Oils, Oleochemicals & Surfactants Technology, Institute of Chemical Technology, Matunga, Mumbai-400019, India
     

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Nano-emulsions are obtained when the size of an emulsion globule reaches approximately 20-500 nm. The small droplet size can resist the physical destabilization caused by gravitational separation, flocculation and coalescence. It also avoids the creaming process because the droplet's Brownian motion is enough to overcome the gravitational separation force present characteristics and properties which depend on composition and the preparation method. Although interest in nano-emulsions was developed since about 20 years ago, mainly for nanoparticle preparation, it is in the last years that direct applications of nano-emulsions in consumer products are being developed, mainly in pharmacy and cosmetics. Nanoemulsion show great promise for the future of cosmetics, diagnostics, drug therapies and biotechnologies, emulsion fuel. The formation, properties and applications of nano-emulsions (also referred to as miniemulsions, ultrafine emulsions, and submicron emulsions) are reviewed and summarized. Nano-emulsion droplet sizes fall typically in the range of 20–200 nm and show narrow size distributions. Although most of the publications on either oil-in-water (O/W) or water-in-oil (W/O) nano-emulsions report their formation by dispersion or high-energy emulsification methods, an increased interest is observed in the study of nano-emulsion formation by condensation or low-energy emulsification methods (based on the phase transitions that take place during the emulsification process). Aim of this review is focus on nanoemulsion advantage and disadvantage, various methods of preparation, characterization techniques and the various new applications of sub micron size emulsion in different areas.

Keywords

Nanoemulsion, Cosmetics, Diagnostics, Drug Therapies, Biotechnologies, Emulsion Fuel.
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  • Nanoemulsion: Current State and perspectives

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Authors

Harshal Patil
Department of Oils, Oleochemicals & Surfactants Technology, Institute of Chemical Technology, Matunga, Mumbai-400019, India
Jyotsna Waghmare
Department of Oils, Oleochemicals & Surfactants Technology, Institute of Chemical Technology, Matunga, Mumbai-400019, India

Abstract


Nano-emulsions are obtained when the size of an emulsion globule reaches approximately 20-500 nm. The small droplet size can resist the physical destabilization caused by gravitational separation, flocculation and coalescence. It also avoids the creaming process because the droplet's Brownian motion is enough to overcome the gravitational separation force present characteristics and properties which depend on composition and the preparation method. Although interest in nano-emulsions was developed since about 20 years ago, mainly for nanoparticle preparation, it is in the last years that direct applications of nano-emulsions in consumer products are being developed, mainly in pharmacy and cosmetics. Nanoemulsion show great promise for the future of cosmetics, diagnostics, drug therapies and biotechnologies, emulsion fuel. The formation, properties and applications of nano-emulsions (also referred to as miniemulsions, ultrafine emulsions, and submicron emulsions) are reviewed and summarized. Nano-emulsion droplet sizes fall typically in the range of 20–200 nm and show narrow size distributions. Although most of the publications on either oil-in-water (O/W) or water-in-oil (W/O) nano-emulsions report their formation by dispersion or high-energy emulsification methods, an increased interest is observed in the study of nano-emulsion formation by condensation or low-energy emulsification methods (based on the phase transitions that take place during the emulsification process). Aim of this review is focus on nanoemulsion advantage and disadvantage, various methods of preparation, characterization techniques and the various new applications of sub micron size emulsion in different areas.

Keywords


Nanoemulsion, Cosmetics, Diagnostics, Drug Therapies, Biotechnologies, Emulsion Fuel.

References