Micro-albuminuria & CRP-Early Mortality Marker in ACS

This study was performed in 60 Acute MI patient, Non-diabetic, admited within 24 hr of chest pain, to investigate the prevalence & significance of Micro Albuminuria (MAU) & CRP as a predictor of inhospital mortality & to correlate it with other prognostic markers. Serial spot urinary Alb/Crt Ratio (ACR) measured from Day 1 to Day 7 along with hemodynamic measurement clinically by Killip'S class & EF by ECHO. Total 7 days mortality was recorded. Microalbumin (>30μg/mg) was found in 95% of patient on day 1. Groups with higher MAU (>100μg/mg) on day 1 was associated with high mortality(p<0.01). Increasing or static MAU had a positive correlation with deteriorating Killip'S class along with direct correlation with decrease in LVEF serially from Day 1 to Day 7. Thus MAU was found to be a reliable predictor of short term in-hospital mortality in ACS patient.