International Journal of Contemporary Medicine

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A Study of Role of Tacrolimus in the Treatment of Lichen Planus


Affiliations
1 Dept of Oral Medicine and Radiology, Dr. D. Y Patil Dental College and Hospital, Navi Mumbai, Maharashtra, India
     

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Oral lichen planus is a chronic inflammatory immunological reaction in which epidermal or epithelial basal cell damage produces mucocutaneous lesions of various types anticipated to occur in 0.5 to 1 % of adult individuals of the middle ages, consequential in mucosal ulceration and scarring. The basis of this study is to explore the usefulness of tacrolimus to treat the oral lesion of lichen planus. Consequently, in the present study we have included a group of patients having oral lichen planus, we intend to uncover a collateral therapy for oral lichen planus other than corticosteroids which has been the mainstay of treatment since their introduction decades ago.

Keywords

Lichen Planus, Tacrolimus, Immunomodulators.
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  • A Study of Role of Tacrolimus in the Treatment of Lichen Planus

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Authors

Runuk Singhi
Dept of Oral Medicine and Radiology, Dr. D. Y Patil Dental College and Hospital, Navi Mumbai, Maharashtra, India
Sonal Vahanwala
Dept of Oral Medicine and Radiology, Dr. D. Y Patil Dental College and Hospital, Navi Mumbai, Maharashtra, India
Sandeep Pagare
Dept of Oral Medicine and Radiology, Dr. D. Y Patil Dental College and Hospital, Navi Mumbai, Maharashtra, India

Abstract


Oral lichen planus is a chronic inflammatory immunological reaction in which epidermal or epithelial basal cell damage produces mucocutaneous lesions of various types anticipated to occur in 0.5 to 1 % of adult individuals of the middle ages, consequential in mucosal ulceration and scarring. The basis of this study is to explore the usefulness of tacrolimus to treat the oral lesion of lichen planus. Consequently, in the present study we have included a group of patients having oral lichen planus, we intend to uncover a collateral therapy for oral lichen planus other than corticosteroids which has been the mainstay of treatment since their introduction decades ago.

Keywords


Lichen Planus, Tacrolimus, Immunomodulators.

References