International Journal of Contemporary Medicine

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Metabolic Syndrome in Perimenopausal and Menopausal Women- A Cross Sectional Study


Affiliations
1 Sri Siddhartha Medical College, Tumkur, Karnataka, India
     

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There is an increased incidence of Metabolic Syndrome across the globe. Metabolic Syndrome a strong predictor of coronary vascular disorder and Diabetes Mellitus is not highlighted enough especially in post menopausal women. This study was undertaken to learn the prevalence of Metabolic Syndrome in perimenopausal and menopausal women. A detailed history, clinical examination along with mini glucose tolerance test, FBS and PPBS in a known diabetic and fasting lipid profile were done in 696 women. Among them 208 (29.88%) are in perimenopausal group and 488 (70.11%) are in post menopause group. Metabolic Syndrome was defined using Modified NCEP ATP III Criteria. Metabolic syndrome was found in 468 (67.24%) among them 131 (28%) are in perimenopausal group and 337 (72%) are in post menopausal group. Age group of women with Metabolic Syndrome in the range 40-44 years were 65 (13.88%), 45-49 years were 86 (18.37%), 50-54 years were 65 (13.88%), 55-60 years were 128 (27.35%), 60-65 years were 49 (10.47%) and 66 years and above were 75 (16.02%). Considering the individual components of Metabolic Syndrome Waist circumference was ≥ 80 cm in 365 (77.99%), Systolic blood pressure was ≥ 130 mm Hg in 396 (84.61%), Diastolic blood pressure was ≥ 85 mm Hg in 293 (62.60%), Triglycerides were ≥ 150 mg/dl in 277 (59.18%), High density lipoproteins were ≥ 50 mg/dl in 421 (89.95%) and Fasting blood sugars were ≥ 110 mg/dl in 121 (25.85%). Our study showed increased prevalence of Metabolic Syndrome in post menopausal women.

Keywords

Diastolic Blood Pressure, Fasting Blood Sugar, High Density Lipoprotein, Metabolic Syndrome, Perimenopausal Women, Post Menopausal Women, Systolic Blood Pressure, Triglycerides, Waist Circumference.
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  • Howkins and Bourne. Perimenopause, Menopause, Premature menopause and Post menopausal bleeding. In: Padubidri, Daftary, editors. Shaw’s text book of gynaecology. 15th ed. Haryana: Elseivier; 2011:61-74

  • Jeffcoates. Menopause. In: Kumar P, Malhotra N, editor. Principles of Gynaecology. 7th ed. Newdelhi: Jaypee; 2008:862-83

  • Gohlke-Barwolf C. Coronary artery disease: Is menopause a risk factor?, Basic res Cardiol.2000;95:177-83

  • Dorum A, Tonstad S, Liavaag AH, Michelsen TM, Hildrum B, Dahl AA. Bilateral oophorectomy before 50 years of age is significantly associated with matebolic syndrome and Framingham risk score; A controlled population based study (HUNT-2) Gynecol oncol.20058;109:377-83

  • Eckel RH. The Metabolic Syndrome. In: Longo DL et al, Harrison’s Principles of Internal Medicine, 18th ed: Mc Graw Hill; 2012:1992

  • Misra A. Metabolic Syndrome. In: Munjal YP, API Textbook of Medicine, 9th ed, Vol 2: Jaypee Brothers; 2012:1279-80

  • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106: 3143-421.

  • Pandey S, Srinivas M, Agashe S, Joshi J, Galvankar P, Prakasam CP.et.al. Menopause and metabolic syndrome: A study of 498 urban women from western India. Journal of Midlife Health. 2010 Jul-Dec;1(2):63-69

  • Jesmin S, Islam AMS, Akter S, Islam M, Sultana NS, Yamaguchi N.et.al. Metabolic syndrome among pre and post menopausal rural women in Bangladesh: result from a population based study. BMC Research Notes. 2013 Apr 18;6:157

  • Jouyandeh Z, Nayabzadeh F, Qorbani M, Asadi M. Metabolic Syndrome and Menopause. Journal of Diabetes and Metabolic Syndrome. 2013 Jan 3;12:1

  • Mesch VR, Siseles NO, Maidana PN, Boero LE, Sayegh F, Prada M, et.al. Androgens in relationship to cardiovascular risk factor in the menopausal transition. Climateric. 2008;13:83-91


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  • Metabolic Syndrome in Perimenopausal and Menopausal Women- A Cross Sectional Study

Abstract Views: 389  |  PDF Views: 0

Authors

M Shalini
Sri Siddhartha Medical College, Tumkur, Karnataka, India
K Mounika
Sri Siddhartha Medical College, Tumkur, Karnataka, India
B Girish
Sri Siddhartha Medical College, Tumkur, Karnataka, India
KP Suresh Babu
Sri Siddhartha Medical College, Tumkur, Karnataka, India
Hamsaveena
Sri Siddhartha Medical College, Tumkur, Karnataka, India
AG Srinivasa Murthy
Sri Siddhartha Medical College, Tumkur, Karnataka, India

Abstract


There is an increased incidence of Metabolic Syndrome across the globe. Metabolic Syndrome a strong predictor of coronary vascular disorder and Diabetes Mellitus is not highlighted enough especially in post menopausal women. This study was undertaken to learn the prevalence of Metabolic Syndrome in perimenopausal and menopausal women. A detailed history, clinical examination along with mini glucose tolerance test, FBS and PPBS in a known diabetic and fasting lipid profile were done in 696 women. Among them 208 (29.88%) are in perimenopausal group and 488 (70.11%) are in post menopause group. Metabolic Syndrome was defined using Modified NCEP ATP III Criteria. Metabolic syndrome was found in 468 (67.24%) among them 131 (28%) are in perimenopausal group and 337 (72%) are in post menopausal group. Age group of women with Metabolic Syndrome in the range 40-44 years were 65 (13.88%), 45-49 years were 86 (18.37%), 50-54 years were 65 (13.88%), 55-60 years were 128 (27.35%), 60-65 years were 49 (10.47%) and 66 years and above were 75 (16.02%). Considering the individual components of Metabolic Syndrome Waist circumference was ≥ 80 cm in 365 (77.99%), Systolic blood pressure was ≥ 130 mm Hg in 396 (84.61%), Diastolic blood pressure was ≥ 85 mm Hg in 293 (62.60%), Triglycerides were ≥ 150 mg/dl in 277 (59.18%), High density lipoproteins were ≥ 50 mg/dl in 421 (89.95%) and Fasting blood sugars were ≥ 110 mg/dl in 121 (25.85%). Our study showed increased prevalence of Metabolic Syndrome in post menopausal women.

Keywords


Diastolic Blood Pressure, Fasting Blood Sugar, High Density Lipoprotein, Metabolic Syndrome, Perimenopausal Women, Post Menopausal Women, Systolic Blood Pressure, Triglycerides, Waist Circumference.

References