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Posterior Urethral Valve Syndrome: An Uncommon Cause of Intrauterine Fetal Death
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A posterior urethral valve is an obstructing membrane in the posterior part of male urethra leading to renal failure and death occurring in 1:5000 to 8000 male live births. The incidence of intrauterine deaths related to posterior urethral valve is under reported. The cause for the occurrence is unclear. Posterior Urethral Valve syndrome is a syndrome of obstructive uropathy resulting in hypertrophy of bladder, ureters and dysplasia of the kidneys. Prenatal ultrasonography is a gold standard diagnostic tool. The fetal autopsy conducted over the case presented here demonstrates all the classical findings of the obstructive uropathy (renal dysplasia, hydronephrosis, bladder hypertrophy, hydro ureters). The case reiterates the importance of prenatal ultrasonography and meticulous fetal autopsy to determine the cause of intra uterine fetal death.
Keywords
Posterior Urethral Valve Syndrome, Obstructive Uropathy, Fetal Autopsy, Intrauterine Death
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- Manzoni C, Valentini A (2002). “Posterior urethral valves.” Rays 27 (2): 131–4.
- Krishnan A, de Souza A, Konijeti R, Baskin LS. The anatomy and embryology of posterior urethral valves. J Urol 2006; 175:1214-1220.
- “Emedicine - Posterior urethral valves - overview and treatment.”. Emedicine. Retrieved June 23, 2011.
- Abdulrasheed A. Nasir, Emmanuel A. Ameh, Lukman O. Abdur-Rahman, James O. Adeniran, Mohan K. Abraham.”Posterior Urethral Valve. World J Pediatr 2011; 7(3):205-216.
- W. Y. Huang, C. A. Peters, D. Zurakowski et al., “Renal biopsy in congenital ureteropelvic junction obstruction: evidence for parenchymal maldevelopment,” Kidney International, vol. 69, no. 1, pp. 137–143, 2006.
- M. K. Farrugia and A. S. Woolf, “Congenital urinary bladder outlet obstruction,” Fetal and Maternal Medicine Review, vol. 21, no. 1, pp. 55–73, 2010.
- Borzi PA, Beasley SW, Fowler R. Posterior urethral valves in non-twin siblings. Br J Urol 1992; 70:201.
- D. I. Williams and H. B. Eckstein, “Obstructive valves in the posterior urethra,” Journal of Urology, vol. 93, pp. 236–246, 1965.
- Elder JS, Shapio E. Posterior urethral valves. In: Ashcraft KW, Holcomb GW, Murphy JP, eds. Pediatric Surgery, 4th ed. Philadelphia: Elsevier Saunders, 2005: 781-792.
- O. S. Lowsley, “Congenital malformation of the posterior urethra,” Annals of Surgery, vol. 60, no. 6, pp. 733–741, 1914.
- “Nationwide Childrens Hospital, Radiology - Posterior urethral valves”. Nationwide Childrens Hospital. Retrieved July 26, 2010.
- Daniel P. Casella, Jeffrey J. Tomaszewski, and Michael C. Ost. Posterior Urethral Valves: Renal Failure and Prenatal Treatment. IntJnephrology.pp1-4,2012.
- B. A. Thornhill, L. E. Burt, C. Chen, M. S. Forbes, and R. L. Chevalier, “obstruction, “Kidney International, vol. 67, no. 1, pp. 42–52, 2005.
- R. L. Chevalier, B. A. Thornhill, M. S. Forbes, and S. C. Kiley, “Mechanisms of renal injury and progression of renal disease in congenital obstructive nephropathy,” Pediatric Nephrology, vol. 25, no. 4, pp. 687–697, 2010.
- S. Decramer, S. Wittke, H. Mischak et al., “Predicting the clinical outcome of congenital unilateral ureteropelvic junction obstruction in newborn by urinary proteome analysis,” Nature Medicine, vol. 12, no. 4, pp. 398–400, 2006.
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