Indian Journal of Public Health Research & Development

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A Study of Biochemical Changes in Occupational Exposure of Portland Cement among Construction Workers in Ujjain, Madhya Pradesh


Affiliations
1 Department of Biochemistry, Saraswathi Institute of Medical Sciences Pilkhuwa, Hapur, Dist Gaziabad (UP), India
2 Dept of Biochemistry, SBH Govt. Medical College, Dhule (Maharashtra), India
3 Dept of Biochemistry, L T M Medical College & Hospital, Sion, Mumbai (Maharashtra), India
     

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Cement used in building and various construction works is a complex mixture of several metal oxides, silicates and miscellaneous compounds. In India, laborers involved in construction work are constantly exposed to the cement various ways. Biochemical effects of the occupational exposure in 31 workers were assessed by Aspartate transaminase, Alanine transaminase, Calcium, Magnesium, Maolondialdehyde and Ascorbate levels in serum. It was found that serum ALT, AST and calcium levels were elevated as compared to the controls. The Dirties ratio was significantly higher in the workers. The lipid peroxidation index was higher while ascorbate level was significantly lower in the cases. It is concluded that the construction worker show marginal alteration in liver functions which is secondary to oxidative stress generated by complex interaction of toxic cement compounds.

Keywords

Cement, Alanine Transaminase, Aspartate Transaminase, Calcium Magnesium, Maolondialdehyde, Ascorbic Acid
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  • A Study of Biochemical Changes in Occupational Exposure of Portland Cement among Construction Workers in Ujjain, Madhya Pradesh

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Authors

A Y Mane
Department of Biochemistry, Saraswathi Institute of Medical Sciences Pilkhuwa, Hapur, Dist Gaziabad (UP), India
V R Bhagwat
Dept of Biochemistry, SBH Govt. Medical College, Dhule (Maharashtra), India
S D Mane
Dept of Biochemistry, L T M Medical College & Hospital, Sion, Mumbai (Maharashtra), India

Abstract


Cement used in building and various construction works is a complex mixture of several metal oxides, silicates and miscellaneous compounds. In India, laborers involved in construction work are constantly exposed to the cement various ways. Biochemical effects of the occupational exposure in 31 workers were assessed by Aspartate transaminase, Alanine transaminase, Calcium, Magnesium, Maolondialdehyde and Ascorbate levels in serum. It was found that serum ALT, AST and calcium levels were elevated as compared to the controls. The Dirties ratio was significantly higher in the workers. The lipid peroxidation index was higher while ascorbate level was significantly lower in the cases. It is concluded that the construction worker show marginal alteration in liver functions which is secondary to oxidative stress generated by complex interaction of toxic cement compounds.

Keywords


Cement, Alanine Transaminase, Aspartate Transaminase, Calcium Magnesium, Maolondialdehyde, Ascorbic Acid

References