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BIND Syndrome - a Life Threatening Sequel to Kernicterus
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Bilirubin Induced Neurological Dysfunction Syndrome (BIND) Syndrome is a condition caused by bilirubin toxicity to the basal ganglia, hippocampus and various brainstem nuclei. In the acute phase, severely jaundiced infants become lethargic, hypotonic and suck poorly. If the hyperbilirubinemia is not treated, the infant becomes hypertonic and may develop a fever and a high-pitched cry.[1] The hypertonia is manifested by backward arching of the neck (retrocollis) and trunk (opisthotonus). Surviving infants usually develop a severe form of choreoathetoid cerebral palsy, hearing loss, dental dysplasia, paralysis of upward gaze and, less often, intellectual and other handicaps.[2] Hereby presenting a rare case report of a 9 year old female patient having BIND Syndrome with typical dental manifestations.
Keywords
BIND Syndrome, Kernicterus, Hyperbilirubinemia, Dental Dysplasia, Cerebral Palsy
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