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Effect of Alcoholic Extract of Withania somnifera Linn Roots on Reproductive Organs in Streptozotocin Induced Diabetic Rats


Affiliations
1 Department of Physiology, Jawaharlal Nehru Medical College, KLE University, Belgaum, India
2 Department of Physiology, Shri Sathya Sai Medical College & RI, Tiruporur, Tamilnadu, India
3 Department of Anatomy, Jawaharlal Nehru Medical College, KLE University, Belgaum, India
     

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"Effect of alcoholic extract of Withania somnifera linn ischolar_mains on reproductive organs in streptozotocin induced diabetic rats." Withania somnifera linn(WS) is a perennial herb used in various Ayurvedic treatment procedures. Its role over the reproductive system is less studied especially in the diabetic.

Aim

1.To rule out the effect of WS alcoholic ischolar_main extract over the weight of the reproductive organs of Streptozotocin induced diabetic male rats.

2.To rule out the plants ability to increase the sperm count.

Material and methods

Twenty four adult male albino rats were grouped into four groups. Diabetes induced by injecting a single dose of Streptozotocin (50mg/kg BW) intraperitoneally. Insulin was given to one group with 5 units/Kg BW intraperitoneally for 30 days. Alcoholic ischolar_main extract of WS (500mg/Kg) was given to another diabetic group orally for 30days. Blood sugar, Body weight, Weight of Testes, Cauda epididymis and Caudal Sperm count was determined on 31st day. Data collected were statistically analysed using SPSS ver. 15.0 software.

Results

Statistically significant improvement in terms of testes weight and Caudal sperm count was obtained in Wsomnifera treated diabetic rats than that of insulin treated.

Conclusion

Withania somnifera ischolar_main extracts had the potency to increase the reproductive efficiency of the diabetic rats.


Keywords

Diabetes, Testes Weight, Cauda Epididymis
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  • Effect of Alcoholic Extract of Withania somnifera Linn Roots on Reproductive Organs in Streptozotocin Induced Diabetic Rats

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Authors

R. Rajashree
Department of Physiology, Jawaharlal Nehru Medical College, KLE University, Belgaum, India
M. I. Glad Mohesh
Department of Physiology, Shri Sathya Sai Medical College & RI, Tiruporur, Tamilnadu, India
M. V. Ravishankar
Department of Anatomy, Jawaharlal Nehru Medical College, KLE University, Belgaum, India
Prema Sembulingam
Department of Physiology, Shri Sathya Sai Medical College & RI, Tiruporur, Tamilnadu, India

Abstract


"Effect of alcoholic extract of Withania somnifera linn ischolar_mains on reproductive organs in streptozotocin induced diabetic rats." Withania somnifera linn(WS) is a perennial herb used in various Ayurvedic treatment procedures. Its role over the reproductive system is less studied especially in the diabetic.

Aim

1.To rule out the effect of WS alcoholic ischolar_main extract over the weight of the reproductive organs of Streptozotocin induced diabetic male rats.

2.To rule out the plants ability to increase the sperm count.

Material and methods

Twenty four adult male albino rats were grouped into four groups. Diabetes induced by injecting a single dose of Streptozotocin (50mg/kg BW) intraperitoneally. Insulin was given to one group with 5 units/Kg BW intraperitoneally for 30 days. Alcoholic ischolar_main extract of WS (500mg/Kg) was given to another diabetic group orally for 30days. Blood sugar, Body weight, Weight of Testes, Cauda epididymis and Caudal Sperm count was determined on 31st day. Data collected were statistically analysed using SPSS ver. 15.0 software.

Results

Statistically significant improvement in terms of testes weight and Caudal sperm count was obtained in Wsomnifera treated diabetic rats than that of insulin treated.

Conclusion

Withania somnifera ischolar_main extracts had the potency to increase the reproductive efficiency of the diabetic rats.


Keywords


Diabetes, Testes Weight, Cauda Epididymis

References