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Study the Effect of Cadmium Chloride on the Histological Structure and Biochemical Enzymes in Male White Mice


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1 Department of Biology, College of Science, University of Babylon, Iraq
     

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Cadmium presence as a toxic substance come in to body as contamination of water, air and food its also found in cigarette smoking. There for the present study down to investigate the effect of cdcl2 on the liver function and enzyme of kidney and studing the histological structure of kidney and liver. In the experiment we used eighteen male white mice and injected subcutenous for 40 days. The results shown asignificant increase in GOT and GPT fortreated groups (5,10) mg/kg as compared to control group. As for the blood urea and serum creatinine we found asignificant increase for treated groups as compared to control group. Thisresults confident by the histological study of liver and kidney, The results shown a bleeding in liver, lysis, necrosis and hypertrophy as compared to control group.as for the kidney texture we found alysis in distal tubules of kidney as compared to control group.

Keywords

Cadmium, Mice, Liver, Kidney, Histology.
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  • Study the Effect of Cadmium Chloride on the Histological Structure and Biochemical Enzymes in Male White Mice

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Authors

Jenan Mahdi Jwad
Department of Biology, College of Science, University of Babylon, Iraq

Abstract


Cadmium presence as a toxic substance come in to body as contamination of water, air and food its also found in cigarette smoking. There for the present study down to investigate the effect of cdcl2 on the liver function and enzyme of kidney and studing the histological structure of kidney and liver. In the experiment we used eighteen male white mice and injected subcutenous for 40 days. The results shown asignificant increase in GOT and GPT fortreated groups (5,10) mg/kg as compared to control group. As for the blood urea and serum creatinine we found asignificant increase for treated groups as compared to control group. Thisresults confident by the histological study of liver and kidney, The results shown a bleeding in liver, lysis, necrosis and hypertrophy as compared to control group.as for the kidney texture we found alysis in distal tubules of kidney as compared to control group.

Keywords


Cadmium, Mice, Liver, Kidney, Histology.

References