Research Journal of Pharmacy and Technology

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Synthesis and Characterization of Some new Heterocyclic Compounds Containing a Sulfonamide Moiety


Affiliations
1 Department of Chemistry, College of Education for Girls, University of Kufa, Iraq
     

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This study deliberates a sequence of 3-hydroxy-4-aminobenzene sulfonamide derivatives. In the present investigation 3-hydroxy-4-aminobenzene sulfonamide has been taken as initial material and treated with acetylacetone to prepare new azo compound then azo compound reacts with p-chloro benzaldehyde in absolute ethanol to prepare chalcone derivatives then chalcone derivatives react with various compounds such as urea thiourea, quandin, Meldrum's acid, barbituric acid, hydroxyl amine hydrochloride, 2,4-dinitrophenyl hydrazine to prepare new heterocyclic compound.

Keywords

4-Aminobenzene Sulfonamide, Azo Compound, Chalcone Derivatives, Heterocyclic Compounds.
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  • Synthesis and Characterization of Some new Heterocyclic Compounds Containing a Sulfonamide Moiety

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Authors

Hanan Falah Mohsein
Department of Chemistry, College of Education for Girls, University of Kufa, Iraq
Nadia Sadiq Majeed
Department of Chemistry, College of Education for Girls, University of Kufa, Iraq
Thanaa Abed Al-Ameerhelal
Department of Chemistry, College of Education for Girls, University of Kufa, Iraq

Abstract


This study deliberates a sequence of 3-hydroxy-4-aminobenzene sulfonamide derivatives. In the present investigation 3-hydroxy-4-aminobenzene sulfonamide has been taken as initial material and treated with acetylacetone to prepare new azo compound then azo compound reacts with p-chloro benzaldehyde in absolute ethanol to prepare chalcone derivatives then chalcone derivatives react with various compounds such as urea thiourea, quandin, Meldrum's acid, barbituric acid, hydroxyl amine hydrochloride, 2,4-dinitrophenyl hydrazine to prepare new heterocyclic compound.

Keywords


4-Aminobenzene Sulfonamide, Azo Compound, Chalcone Derivatives, Heterocyclic Compounds.

References