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Evaluation of Antihyperlipidemic Activity of Leaves of Cassia Tora


Affiliations
1 Assistant Professors, KVSR Siddhartha college of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh., India
2 Assistant Professors, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
3 IV B Pharmacy Students, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
     

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Aim: To evaluate the antihyperlipidemic activity of leaves of cassia tora Objective: Hyperlipidemia is a clinical condition causing lethal diseases like atherosclerosis, myocardial infarction etc that ultimately leads to death. Several works have been reported that the extracts of many plants have antihyperlipidemic activity. Cassia tora is used for a long time as a daily vegetable in many countries. It consists of phytochemical constituents like flavonoids which lowers blood cholesterol level. Materials and Methods: Materials used: Antihyperlipidemic activity of Cassia tora was screened by a model, Cholesterol diet induced hyperlipidemia. Marker enzymes like LDH, LDL, VLDL, total protein, total cholesterol, AST, ALP, ALT,SOD, Catalase, LPO and histopathology of myocardium and aorta carried out. Results: Flavonoids of leaves of Cassia tora treated group showed significant decrease in LDL-Cholesterol, total cholesterol, triglycerides, AST, ALT, ALP and increase in HDL cholesterol, albumin, total protein and further was concluded by histopathological studies. Conclusion: From result, it was concluded that flavonoid of leaves of Cassia tora shows antihyperlipidemic activity in the heart of rats.

Keywords

Antihyperlipidemic, Hypercholesteremia, Cholesterol-diet, Atherosclerosis, Myocardial infarction.
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  • Evaluation of Antihyperlipidemic Activity of Leaves of Cassia Tora

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Authors

Iswarya Obilineni
Assistant Professors, KVSR Siddhartha college of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh., India
Jangam Divya Latha
Assistant Professors, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
Kamireddy Srikala
Assistant Professors, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
Gummadi Asha
IV B Pharmacy Students, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
Marupilla Amulya
IV B Pharmacy Students, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India
Vaddeswarapu Rajani
Assistant Professors, Nirmala College of Pharmacy, Atmakur, Andhra Pradesh., India

Abstract


Aim: To evaluate the antihyperlipidemic activity of leaves of cassia tora Objective: Hyperlipidemia is a clinical condition causing lethal diseases like atherosclerosis, myocardial infarction etc that ultimately leads to death. Several works have been reported that the extracts of many plants have antihyperlipidemic activity. Cassia tora is used for a long time as a daily vegetable in many countries. It consists of phytochemical constituents like flavonoids which lowers blood cholesterol level. Materials and Methods: Materials used: Antihyperlipidemic activity of Cassia tora was screened by a model, Cholesterol diet induced hyperlipidemia. Marker enzymes like LDH, LDL, VLDL, total protein, total cholesterol, AST, ALP, ALT,SOD, Catalase, LPO and histopathology of myocardium and aorta carried out. Results: Flavonoids of leaves of Cassia tora treated group showed significant decrease in LDL-Cholesterol, total cholesterol, triglycerides, AST, ALT, ALP and increase in HDL cholesterol, albumin, total protein and further was concluded by histopathological studies. Conclusion: From result, it was concluded that flavonoid of leaves of Cassia tora shows antihyperlipidemic activity in the heart of rats.

Keywords


Antihyperlipidemic, Hypercholesteremia, Cholesterol-diet, Atherosclerosis, Myocardial infarction.

References