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In-vivo Anticancer Activity of Ethanol Extract of Brassica Oleracea var. Italica (Broccoli) Against Dalton’s Lymphoma Ascites Induced Cancer Using Female Swiss Albino Mice


Affiliations
1 Department of Foods and Nutrition, Vellalar College for Women, Erode – 638012, Tamil Nadu, India
 

The study aimed at evaluating the effect of Ethanol Extract of Brassica Oleracea var. Italica (EEBO) against Dalton’s Ascitic Lymphoma (DAL) in Swiss Albino mice. The mice were injected with DAL cells (106 cells/mouse) intraperitoneally, followed by treatment with EEBO for 14 days at a dosage of 200mg and 500mg/kg. A significant decrease in the cancer cell number, tumour weight, tumour volume and increased life span of mice were observed. These results suggested the protective effect of EEBO against DAL.

Keywords

Anticancer Activity, Brassica Oleracea var. Italica, Dalton’s Ascitic Lymphoma Swiss Albino Mice.
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  • In-vivo Anticancer Activity of Ethanol Extract of Brassica Oleracea var. Italica (Broccoli) Against Dalton’s Lymphoma Ascites Induced Cancer Using Female Swiss Albino Mice

Abstract Views: 576  |  PDF Views: 263

Authors

P. Indumathy
Department of Foods and Nutrition, Vellalar College for Women, Erode – 638012, Tamil Nadu, India
G. Shanthini
Department of Foods and Nutrition, Vellalar College for Women, Erode – 638012, Tamil Nadu, India

Abstract


The study aimed at evaluating the effect of Ethanol Extract of Brassica Oleracea var. Italica (EEBO) against Dalton’s Ascitic Lymphoma (DAL) in Swiss Albino mice. The mice were injected with DAL cells (106 cells/mouse) intraperitoneally, followed by treatment with EEBO for 14 days at a dosage of 200mg and 500mg/kg. A significant decrease in the cancer cell number, tumour weight, tumour volume and increased life span of mice were observed. These results suggested the protective effect of EEBO against DAL.

Keywords


Anticancer Activity, Brassica Oleracea var. Italica, Dalton’s Ascitic Lymphoma Swiss Albino Mice.

References





DOI: https://doi.org/10.15613/fijrfn%2F2020%2Fv7i2%2F207176