Effect of P. serratifolia Leaf Extract on Hematological Parameters and Standarization of Snacks using P. serratifolia Leaf Powder
Premna serratifolia (also known as Pachumullai) belongs to the family Verbenaceae, is a medicinal plant known as Agnimantha in Ayurveda. It has potential hepatoprotective and cytotoxic activity. There are many phytochemical and bioactive compounds present in the plant parts of Premna serratifolia. In addition to this, it has higher antioxidant and antimicrobial activity which is beneficial to human health as a therapeutic adjuvant. However, the nutritional components in P. serratifolia have not been probed, though it was consumed during special rituals. Further the anti-anemic effect of P. serratifolia was not yet studied. The present research aimed at assessing the micronutrients (Iron, Phosphorus, Calcium, Ascorbic acid) in P. serratifolia leaf, and the ethanolic extract of P. serratifolia leaf at two different dosage (100mg and 200mg) was examined for hematological parameters (Hemoglobin, Red Blood Cell count and Mean Corpuscular Hemoglobin) in anemic rats and the value added snacks like biscuit, vadam and murukku were formulated at two different ratios by using P. serratifolia leaf powder. The results showed that P. serratifolia leaf extract had higher impact on the hematological parameters when compared with standard drug ferrous fumarate and the higher incorporation of P. serratifolia leaf powder helped to increase the nutrient content in formulated snacks.
Keywords
- Biradar SS, Biradar SP. Alatagi AC, Wantamutte AS and Malur PR. Prevalence of anemia among adolescent girls, a one year cross sectional study, Journal of Clinical and Diagnostic Reasearch. 2012; 6(3):372–7.
- Zhang AS and Enns CA. Molecular mechanisms of normal iron homeostasis. Hematology American Society, Hematology Education Program. 2009; 1:207–14.
- Pandey M, Rohit K, Verma and Shubhini AS. Nutraceuticals new era of medicine and health. Asian Journal of Pharmaceutical and Clinical Research. 2010; 3(1):11– 15.
- Biesalski HK. Nutraceuticals: The link between nutrition and medicine. Kramer K, Hoppe PP, Pocker L, editors. Nutraceuticals in health and diseases prevention New York. Marcel Dekker. 2001; p. 1–26. https://doi.org/10.1201/9780203908174.ch1.PMid:11370660
- Rekha R. Antimicrobial activity of different bark and wood of Premna serratifolia Lin. 2010. International Journal of Pharma and Bio Sciences. 2010; 6(1):1–9.
- Warrier PK, Nambiar VP, Ramankutty C. Indian Medicinal Plants. A compendium of 500 species, India. Orient Longman Publications. 1995; 4:348–52.
- Kala SMU, Balasubramanian T, Soris T and Mohan VR. GC-MS determination of bioactive components of Eugenia singampattianaBedd. International Journal of ChemTech Research. 2011; 3:1534–7.
- Singh RC. Antimicrobial effect of callus and natural plant extracts of premnaserratifolia L. International Journal of Pharmaceutical and Biomedical Research. 2011; 2:17– 20.
- Selvam TN, Venkatakrishnan V, Damoder KS, Elumalai P. Antioxidant and tumor cell suppression potential of Premnaserratifolia Linn. leaf. Toxicology International. 2012; 19:31–4. https://doi.org/10.4103/0971-6580.94514.PMid:22736900 PMCid:PMC3339242
Abstract Views: 864
PDF Views: 361