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Inhibition of Collagen Induced Platelet Aggregation by Wood Apple Extracts


Affiliations
1 Dept of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 020, India
2 Dept of Fruits and Vegetable Technology, Central Food Technological Research Institute, Mysore 570 020, India
     

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Fruits are undoubtedly man's oldest food. Some of the fruits like date palm and pomegranate have been cultivated from 7000 BC. These fruits are rich sources of vitamins, trace minerals, dietary fiber as well as a wide variety of biologically active compounds. A variety of phytonutrients found are carotenoids, polyphenols, anthocyanins, flavanoids, isothiocyanates, sulfides and phytosterols. All these natural compounds have overlapping and complementary biological functions at cellular level providing protection to body from conditions like cancer, cardiovascular diseases, stroke, osteoporosis, muscular degeneration and cataracts. Also they are rich sources of antioxidants. Consumption of pomegronate juice reduced oxidative stress and showed anti-atherogenic properties by inhibiting platelet aggregation. Phenolic components of olive oil affected platelet aggregation by inhibiting Thromboxane B2 (TXB2) and 12-L-hydroperoxyl-5, 8, 10, 14-eicosatetraenoic acid (12-HETE) productions.
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  • Inhibition of Collagen Induced Platelet Aggregation by Wood Apple Extracts

Abstract Views: 294  |  PDF Views: 0

Authors

W. Jessie Suneetha
Dept of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 020, India
M. Siva Prasad
Dept of Fruits and Vegetable Technology, Central Food Technological Research Institute, Mysore 570 020, India
S. M. Aradhya
Dept of Fruits and Vegetable Technology, Central Food Technological Research Institute, Mysore 570 020, India
T. P. Krishnakantha
Dept of Biochemistry and Nutrition, Central Food Technological Research Institute, Mysore 570 020, India

Abstract


Fruits are undoubtedly man's oldest food. Some of the fruits like date palm and pomegranate have been cultivated from 7000 BC. These fruits are rich sources of vitamins, trace minerals, dietary fiber as well as a wide variety of biologically active compounds. A variety of phytonutrients found are carotenoids, polyphenols, anthocyanins, flavanoids, isothiocyanates, sulfides and phytosterols. All these natural compounds have overlapping and complementary biological functions at cellular level providing protection to body from conditions like cancer, cardiovascular diseases, stroke, osteoporosis, muscular degeneration and cataracts. Also they are rich sources of antioxidants. Consumption of pomegronate juice reduced oxidative stress and showed anti-atherogenic properties by inhibiting platelet aggregation. Phenolic components of olive oil affected platelet aggregation by inhibiting Thromboxane B2 (TXB2) and 12-L-hydroperoxyl-5, 8, 10, 14-eicosatetraenoic acid (12-HETE) productions.