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Interrelationship Between Riboflavin and Pyridoxine and Biochemical Aetiology of Lesions of the Mouth


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1 National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania (P.O.), Hyderabad-500 007, India
     

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Several years ago some of my colleagues observed that lesions of the mouth such as angular stomatitis and glossitis respond to treatment with either riboflavin or pyridoxine. This raised the question of the biochemical basis of oral lesions. Wada and Snell have reported that the synthesis of pyridoxal phosphate (PLP) in mammalian tissues depends on the flavin enzyme pyrido xaminephosphate oxidase (PPO).
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  • Interrelationship Between Riboflavin and Pyridoxine and Biochemical Aetiology of Lesions of the Mouth

Abstract Views: 275  |  PDF Views: 1

Authors

M. S. Bamji
National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania (P.O.), Hyderabad-500 007, India
A. V. Laxmi
National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania (P.O.), Hyderabad-500 007, India

Abstract


Several years ago some of my colleagues observed that lesions of the mouth such as angular stomatitis and glossitis respond to treatment with either riboflavin or pyridoxine. This raised the question of the biochemical basis of oral lesions. Wada and Snell have reported that the synthesis of pyridoxal phosphate (PLP) in mammalian tissues depends on the flavin enzyme pyrido xaminephosphate oxidase (PPO).