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Level of Protein in the Diet on Vitamin D, Metabolism and Function in Rats
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It is very well established that physiologically vitamin D 3 to function must undergo sequential hydroxylation, first on C-25 in the liver and subsequently on C-1 in the kidney to form 1,25-dihydroxy cholecalciferol (1,25 (OH) 2 D 3). This final active metabolite of vitamin D 3 is then transported from the site of production to the site of action via a specific transport protein.
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