The Indian Journal of Nutrition and Dietetics

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Level of Protein in the Diet on Vitamin D, Metabolism and Function in Rats


Affiliations
1 National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania P. O., Hyderabad-500007, India
2 College of Agricultural and Life Sciences, University of Wisconsin, Madison, Wisconsin 53706, United States
     

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It is very well established that physiologically vitamin D 3 to function must undergo sequential hydroxylation, first on C-25 in the liver and subsequently on C-1 in the kidney to form 1,25-dihydroxy cholecalciferol (1,25 (OH) 2 D 3). This final active metabolite of vitamin D 3 is then transported from the site of production to the site of action via a specific transport protein.
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  • Level of Protein in the Diet on Vitamin D, Metabolism and Function in Rats

Abstract Views: 219  |  PDF Views: 1

Authors

N. Raghuramulu
National Institute of Nutrition, Indian Council of Medical Research, Jamai-Osmania P. O., Hyderabad-500007, India
H. F. De Luca
College of Agricultural and Life Sciences, University of Wisconsin, Madison, Wisconsin 53706, United States

Abstract


It is very well established that physiologically vitamin D 3 to function must undergo sequential hydroxylation, first on C-25 in the liver and subsequently on C-1 in the kidney to form 1,25-dihydroxy cholecalciferol (1,25 (OH) 2 D 3). This final active metabolite of vitamin D 3 is then transported from the site of production to the site of action via a specific transport protein.