Effect of High Cholesterol Diet on Liver Enzymes and Blood and Liver Glutathione

Activities of various enzymes in animal tissues are affected by nutritional alterations. Miller and Williams reported a marked decrease in the activities of hepatic enzymes during protein depletion. Szepesi and Freedland reported a marked decrease in the activities of hepatic enzymes such as alanine aminotransferase, aspartate aminotransferase and certain other enzymes when high carbohydrate diet was fed to rats previously adapted to high protein diet.