The Indian Journal of Nutrition and Dietetics

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Resistant Starch Supplementation Improves Bifidobacteria Colonization and Lipid Profile in Adult Obese Subjects Residing in Urban Vadodara


Affiliations
1 Department of Foods and Nutrition, The Maharaja Sayajirao University of Baroda, Vadodara, India
     

   Subscribe/Renew Journal


Obesity continues to be a growing problem globally among all age groups, further associated with life threatening co-morbidities. Resistant Starch (RS) as a dietary component has been recently recognized as a prebiotic with potential role in improving the bacterial ecology of human gut. The present study was undertaken to evaluate the impact of resistant starch supplementation by the obese adults in urban Vadodara on microbial changes in gut flora with respect to Bifidobacteria and Enterobacteria. Using a non randomised control trial study design, 60 obese adults were enrolled from the free living population of urban Vadodara. Baseline information was collected and subjects were classified into control (n=30) and experimental group (n=30). Experimental group was supplemented with 10 g of RS daily for the period of two months (60 days). The control group were not given anything during this period. Blood and stool samples were analysed for lipid profile and the presence of Bifidobacteria and pathogenic Enterobacteria, respectively both at baseline and after the intervention period. Results revealed a significant increase in the mean log counts of Bifidobacteria by 11.7% with no significant reduction in the mean log counts of enteric pathogens and lipid profile of subjects. Hence study concludes that a daily supplementation of 10 grams of RS for 60 days to the obese subjects improved colonization of beneficial gut microbiota in terms of Bifidobacteria, but had little effect on obesity.

Keywords

Resistant Starch, Obesity, Bifidobacteria, Enterobacteria, Prebiotic.
User
Notifications

  • World health Organisation (2018). WHO methods and data sources for global burden of disease estimates 2000-2016. Department of Information, Evidence and Research WHO, Geneva.

  • Cummings, J.H., Stephen, A.M. Carbohydrate terminology and classification. Eur. J. Clin.

  • Nutr. 2007, 61, 5–18

  • National family health survey NFHS-3 (2005–06). International Institute for Population Sciences (IIPS) Mumbai. Available from: http://www.rchiips.org/nfhs/nfhs3.shtml

  • Visscher, T.L.S., Snijder, M.B. and Seidell, J.C. Epidemiology: Definition and Classification of Obesity Clinical Obesity in Adults and Children In Kopelman P G, Caterson I.D, Dietz W.H. ED. Clinical Obesity in Adults and Children, 3rd edition, Blackwell Publishing 2010, 3-14.

  • Guarner, F., Bourdet-Sicard, R., Brandtzaeg, P., Gill, H.S., McGuirk, P., van Eden, W., Versalovic, J., Weinstock, J.V. and Rook, G.A. Mechanisms of disease: The hygiene hypothesis revisited. Nat. Clin. Pract. Gastroenterol. Hepatol., 2006, 3, 275-284.

  • Bengmark, S. Ecological control of the gastrointestinal tract: the role of probiotic flora. Gut.

  • , 42, 2–7.

  • Yang, X., Darko, K.O. and Huang, Y. Resistant starch regulates gut microbiota: structure, biochemistry and cell signalling. Cell Physiol. Biochem., 2017, 42, 306-318.

  • Delzene, N.M. and Kok, N. Effects of fructans on lipid metabolism. Am. J. Clin. Nutr., 2001, 73, 456-458.

  • Gibson, G.R. and Roberfroid, M.B. Dietary modulation of the human colonic micro biota introducing the concept of prebiotics. Am. Instit. Nutri., 1995, 32, 0022-3166.

  • Topping, D.L., Fukushima, M. and Bird, A.R. Resistant starch as a prebiotic and symbiotic: state of the art. Pro. Nutr. Soc.. 2003, 62, 171-176.

  • Ahren, B., Mansson, S., Gingerich, R.L. and Havel, P.J. Regulation of plasma leptin in mice: Influence of age, high-fat diet and fasting. Am. J. Physiol., 1997, 273, 113–120.

  • Sajilata, M.G., Singhal, R.S. and Kulkarni, P.R. Resistant starch – A review. Comp. Rev. Fd.Sci. Fd. Safety, 2006, 5, 1-17.

  • Nugent, A.P. Health properties of resistant starch. Nutr. Bull., 30, 27-54. Nutr. 2005, 84, 689–696.

  • Higgins, J.A. Resistant starch: Metabolic effects and potential health benefits. J. AOAC Inter., 2004, 87, 761-768.

  • Anderson, G.H., Catherine, N.L. and Woodend, D.M. Inverse association Asp, N.G. 1992.

  • Resistant starch an update on its physiological effects. Adv. in Ext. Med. Bio., 2002, 427, 200–210.

  • Fuentes-Zaragoza, E., Riquelme-Navarrete, M.J., Sánchez-Zapata, E. and Pérez-Álvarez, J.A. Resistant starch as functional ingredient: A review. Fd. Res. Int., 2010, 43, 931-942.

  • Perera, A., Meda, V. and Tyler, R.T. Resistant starch: A review of analytical protocols for determining resistant starch and of factors affecting the resistant starch content of foods. Fd. Res. Inter., 2010, 43, 1959-1974.

  • Bindels, L.B., Walter, J. and Ramer-Tait, A.E. Resistant starches for the management of metabolic diseases. Curr. Opin. Clin. Nutr., 2015, 18, 559-565.


Abstract Views: 363

PDF Views: 2




  • Resistant Starch Supplementation Improves Bifidobacteria Colonization and Lipid Profile in Adult Obese Subjects Residing in Urban Vadodara

Abstract Views: 363  |  PDF Views: 2

Authors

Mini Sheth
Department of Foods and Nutrition, The Maharaja Sayajirao University of Baroda, Vadodara, India
Aanchal Johari
Department of Foods and Nutrition, The Maharaja Sayajirao University of Baroda, Vadodara, India
Isha Shah
Department of Foods and Nutrition, The Maharaja Sayajirao University of Baroda, Vadodara, India

Abstract


Obesity continues to be a growing problem globally among all age groups, further associated with life threatening co-morbidities. Resistant Starch (RS) as a dietary component has been recently recognized as a prebiotic with potential role in improving the bacterial ecology of human gut. The present study was undertaken to evaluate the impact of resistant starch supplementation by the obese adults in urban Vadodara on microbial changes in gut flora with respect to Bifidobacteria and Enterobacteria. Using a non randomised control trial study design, 60 obese adults were enrolled from the free living population of urban Vadodara. Baseline information was collected and subjects were classified into control (n=30) and experimental group (n=30). Experimental group was supplemented with 10 g of RS daily for the period of two months (60 days). The control group were not given anything during this period. Blood and stool samples were analysed for lipid profile and the presence of Bifidobacteria and pathogenic Enterobacteria, respectively both at baseline and after the intervention period. Results revealed a significant increase in the mean log counts of Bifidobacteria by 11.7% with no significant reduction in the mean log counts of enteric pathogens and lipid profile of subjects. Hence study concludes that a daily supplementation of 10 grams of RS for 60 days to the obese subjects improved colonization of beneficial gut microbiota in terms of Bifidobacteria, but had little effect on obesity.

Keywords


Resistant Starch, Obesity, Bifidobacteria, Enterobacteria, Prebiotic.

References





DOI: https://doi.org/10.21048/ijnd.2018.55.4.22115