The Indian Journal of Nutrition and Dietetics

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Hypovitaminosis-D, Altered Mineral Status and Electrolytes in Severe Falciparum Malaria


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1 Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India
     

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It is known that malaria and undernutrition are interrelated. The aim is to find out the role of vitamin-D and mineral homeostasis and alteration of electrolytes in severe falciparum malaria. Twenty five patients with uncomplicated falciparum malaria and 60 patients with severe falciparum malaria enrolled in the study. The diagnosis of malaria was made by Giemsa stained peripheral blood smear and rapid diagnostic test. Blood was collected for vitamin-D assay, estimation of calcium, phosphate, magnesium, sodium and potassium along with hematological and biochemical tests. The serum level of vitamin-D (27.8 ± 13.6 ng/ml), calcium (8.8 ± 0.5 mg/dl), phosphate (3.1 ± 0.8 mg/dl), magnesium (1.2 ± 1.8 mg/dl), sodium (133.8 ± 11.4 mEq/L) and potassium (3.1 ± 1.9 mEq/L) were found low among patients with severe malaria. Therefore, the supplement of vitamin-D, minerals and electrolytes may improve mortality and morbidity.

Keywords

Vitamin-D, Undernutrition, Malaria, Giemsa Stained Peripheral Blood, Biochemical Tests, Morbidity.
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  • Hypovitaminosis-D, Altered Mineral Status and Electrolytes in Severe Falciparum Malaria

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Authors

Manoj Kumar Mohapatra
Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India
Prafulla Kumar Bariha
Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India
Bunyanananda Padhee
Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India
Biswajit Mohanty
Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India
Subodh Kumar Nayak
Department of General Medicine, VSS Institute of Medical Sciences and Research, Burla, Sambalpur, Odisha - 768 017, India

Abstract


It is known that malaria and undernutrition are interrelated. The aim is to find out the role of vitamin-D and mineral homeostasis and alteration of electrolytes in severe falciparum malaria. Twenty five patients with uncomplicated falciparum malaria and 60 patients with severe falciparum malaria enrolled in the study. The diagnosis of malaria was made by Giemsa stained peripheral blood smear and rapid diagnostic test. Blood was collected for vitamin-D assay, estimation of calcium, phosphate, magnesium, sodium and potassium along with hematological and biochemical tests. The serum level of vitamin-D (27.8 ± 13.6 ng/ml), calcium (8.8 ± 0.5 mg/dl), phosphate (3.1 ± 0.8 mg/dl), magnesium (1.2 ± 1.8 mg/dl), sodium (133.8 ± 11.4 mEq/L) and potassium (3.1 ± 1.9 mEq/L) were found low among patients with severe malaria. Therefore, the supplement of vitamin-D, minerals and electrolytes may improve mortality and morbidity.

Keywords


Vitamin-D, Undernutrition, Malaria, Giemsa Stained Peripheral Blood, Biochemical Tests, Morbidity.

References





DOI: https://doi.org/10.21048/ijnd.2020.57.4.25674