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Systematic Review: Vulnerability of Metabolic Syndrome in COVID-19


Affiliations
1 Department of Dietetics and Applied Nutrition, Amity University Haryana, Gurgaon - 122 412, India
2 Department of Food Science and Nutrition, Banasthali Vidyapith, Rajasthan - 302 001, India
     

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SARS-CoV-2 infection has become a widely spread disease around the world causing rapid hospitalization and death, especially in people with metabolic syndrome. There is very limited literature that goes to present the clinical implications and management of metabolic syndrome in this pandemic. Hence an attempt has been made towards meeting this end. A literature review has been done extracting articles from scopus database following PRISMA guidelines. The manuscripts were studied to identify articles that report metabolic syndrome and its components in COVID-19 infection. A total of 25 manuscripts were included in this systematic review. These studies report systematic inflammation and organ damage in metabolic syndrome that has up regulated SARS-CoV-2 infection. Various treatment strategies have also been suggested and hypothesized. The results of this analysis indicate that patients suffering from metabolic syndrome are vulnerable to COVID-19 owing a sequence of complications.

Keywords

SARS-CoV-2, COVID-19, metabolic syndrome, inflammation, pandemic, infection
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  • Systematic Review: Vulnerability of Metabolic Syndrome in COVID-19

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Authors

Deepika Dhawan
Department of Dietetics and Applied Nutrition, Amity University Haryana, Gurgaon - 122 412, India
Sheel Sharma
Department of Food Science and Nutrition, Banasthali Vidyapith, Rajasthan - 302 001, India

Abstract


SARS-CoV-2 infection has become a widely spread disease around the world causing rapid hospitalization and death, especially in people with metabolic syndrome. There is very limited literature that goes to present the clinical implications and management of metabolic syndrome in this pandemic. Hence an attempt has been made towards meeting this end. A literature review has been done extracting articles from scopus database following PRISMA guidelines. The manuscripts were studied to identify articles that report metabolic syndrome and its components in COVID-19 infection. A total of 25 manuscripts were included in this systematic review. These studies report systematic inflammation and organ damage in metabolic syndrome that has up regulated SARS-CoV-2 infection. Various treatment strategies have also been suggested and hypothesized. The results of this analysis indicate that patients suffering from metabolic syndrome are vulnerable to COVID-19 owing a sequence of complications.

Keywords


SARS-CoV-2, COVID-19, metabolic syndrome, inflammation, pandemic, infection



DOI: https://doi.org/10.21048/IJND.2021.58.3.27233