The Indian Journal of Nutrition and Dietetics

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Role of Physical Activity on Calorie-Induced Changes in Cognition and Depression of Young and Aged Humans


Affiliations
1 Department of Biochemistry, University of Calcutta, Kolkata - 700 019, India
2 Department of Physiology, University of Kalyani, Kalyani, Nadia-741 235, West Bengal, India
     

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Normal aging is known to encounter stress. Association of aging with declining cognition and elevated depression is a phenomenon which can be modulated by lifestyle. Caloric restriction down regulates normal aging by lowering stress and has been found to protect aging processes. The present study assessed the effect of Calorie Restriction (CR) and Physical Activity (PA) on aging-induced changes on cognition and depression. Healthy male aged (20-35 years; N=312) and (55-70 years; N=392) were considered from low income and middle education population. Data related to socioeconomic status, health status, cognitive performance by mini-cog and 6CIT, depression by CES-D Scale, PA Level (PAL) and calorie intake were collected through questionnaires. AP (at-par) diet (amount consumed equivalent to the amount of energy required for 24 h) reduced cognitive function of the aged group compared to the young of the same calorie group without affecting their depression under similar conditions. CR diet improved cognition with a lowering of depression in the young subjects compared to aged of the same group. High PAL in comparison to low PAL irrespective of age and calorie intake positively modulated cognition and depression of the subjects. These results suggest that (a) young population with CR diet and aged population with AP diet are benefitted in both cognitive ability and depression (b) high PAL unlike low PAL improved both cognition and depression of both young and aged population irrespective of their calorie intake.

Keywords

Aging, Calorie Restriction, Cognitive Function, Depression, Physical Activity.
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  • Role of Physical Activity on Calorie-Induced Changes in Cognition and Depression of Young and Aged Humans

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Authors

Aindrila Das
Department of Biochemistry, University of Calcutta, Kolkata - 700 019, India
Samir K. Ghosh
Department of Biochemistry, University of Calcutta, Kolkata - 700 019, India
Goutam Paul
Department of Physiology, University of Kalyani, Kalyani, Nadia-741 235, West Bengal, India
Mrinal K. Poddar
Department of Biochemistry, University of Calcutta, Kolkata - 700 019, India

Abstract


Normal aging is known to encounter stress. Association of aging with declining cognition and elevated depression is a phenomenon which can be modulated by lifestyle. Caloric restriction down regulates normal aging by lowering stress and has been found to protect aging processes. The present study assessed the effect of Calorie Restriction (CR) and Physical Activity (PA) on aging-induced changes on cognition and depression. Healthy male aged (20-35 years; N=312) and (55-70 years; N=392) were considered from low income and middle education population. Data related to socioeconomic status, health status, cognitive performance by mini-cog and 6CIT, depression by CES-D Scale, PA Level (PAL) and calorie intake were collected through questionnaires. AP (at-par) diet (amount consumed equivalent to the amount of energy required for 24 h) reduced cognitive function of the aged group compared to the young of the same calorie group without affecting their depression under similar conditions. CR diet improved cognition with a lowering of depression in the young subjects compared to aged of the same group. High PAL in comparison to low PAL irrespective of age and calorie intake positively modulated cognition and depression of the subjects. These results suggest that (a) young population with CR diet and aged population with AP diet are benefitted in both cognitive ability and depression (b) high PAL unlike low PAL improved both cognition and depression of both young and aged population irrespective of their calorie intake.

Keywords


Aging, Calorie Restriction, Cognitive Function, Depression, Physical Activity.

References