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Efficacy Trials of Sorghum based Composite Flour Mix on the Blood Glucose Levels of Experimental Induced Hyperglycemic Rats


Affiliations
1 Department of Food Science and Nutrition, Assam Agricultural University, Jorhat, Assam-785 013, India
2 Department of Pharmacology and Toxicology, Assam Agricultural University, Jorhat, Assam-785 013, India
3 Department of Horticulture, Assam Agricultural University, Jorhat, Assam-785 013, India
     

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Diabetes is global health disorder affecting millions of people worldwide with the largest number of diabetic adults in India ranging around 61.3 million people. Use of indigenous foods has been advocated to reduce the incidence of chronic, diet related non-communicable diseases such as diabetes, obesity and CVD. In the present study an approach was made to develop and assess the functional efficacy of sorghum based composite flour mix for a period of 15 days on blood glucose level of alloxan induced diabetes rats. Out of all the seven groups, Group A showed no significant improvement in the blood sugar level at the end of the supplementation period, Group B showed significant increase in the blood glucose level while Group C showed significant decrease in the blood glucose level along with Groups D, E, F and G fed with sorghum based composite flour mix showed significant decrease in the blood sugar level. Thus it can be concluded that the blood glucose lowering effect of sorghum based composite flour may be due to the in situ composition of the composite flour mix which are potential sources of dietary fibres like cellulose, lignin, phytonutrients including tannins, phenolic acids, anthocyanins, phytosterols, polyphenols, and policosanols. 


Keywords

Non- Communicable Diseases, Blood Glucose Level, Dietary Fibre, Phytonutrients, Obesity, Diabetes
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  • Efficacy Trials of Sorghum based Composite Flour Mix on the Blood Glucose Levels of Experimental Induced Hyperglycemic Rats

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Authors

Manisha Sharma
Department of Food Science and Nutrition, Assam Agricultural University, Jorhat, Assam-785 013, India
Mamoni Das
Department of Food Science and Nutrition, Assam Agricultural University, Jorhat, Assam-785 013, India
Jadav Sarma
Department of Pharmacology and Toxicology, Assam Agricultural University, Jorhat, Assam-785 013, India
Alam S.
Department of Horticulture, Assam Agricultural University, Jorhat, Assam-785 013, India

Abstract


Diabetes is global health disorder affecting millions of people worldwide with the largest number of diabetic adults in India ranging around 61.3 million people. Use of indigenous foods has been advocated to reduce the incidence of chronic, diet related non-communicable diseases such as diabetes, obesity and CVD. In the present study an approach was made to develop and assess the functional efficacy of sorghum based composite flour mix for a period of 15 days on blood glucose level of alloxan induced diabetes rats. Out of all the seven groups, Group A showed no significant improvement in the blood sugar level at the end of the supplementation period, Group B showed significant increase in the blood glucose level while Group C showed significant decrease in the blood glucose level along with Groups D, E, F and G fed with sorghum based composite flour mix showed significant decrease in the blood sugar level. Thus it can be concluded that the blood glucose lowering effect of sorghum based composite flour may be due to the in situ composition of the composite flour mix which are potential sources of dietary fibres like cellulose, lignin, phytonutrients including tannins, phenolic acids, anthocyanins, phytosterols, polyphenols, and policosanols. 


Keywords


Non- Communicable Diseases, Blood Glucose Level, Dietary Fibre, Phytonutrients, Obesity, Diabetes



DOI: https://doi.org/10.21048/IJND.2021.58.2.26727